Anserine and carnosine determination in meat samples by pure micellar liquid chromatography

Gil-Agustı́, Mayte; Esteve‐Romero, Josep; Carda‐Broch, Samuel

doi:10.1016/j.chroma.2007.11.075

Cited by 68 publications

(41 citation statements)

References 20 publications

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“…The concurrent appearance of elevated concentrations of 1-methylhistidine likely resulted from the metabolism of ingested anserine (22), which is found at relatively high concentrations in the muscle of many oily fish species (22,31). Anserine is found at lower concentrations in chicken and turkey breast meat along with carnosine-a related histidine-derived dipeptide (42,43). In contrast, red meats contain relatively low concentrations of anserine, but have relatively high concentrations of carnosine (43,44).…”

Section: Discussionmentioning

confidence: 99%

Use of mass spectrometry fingerprinting to identify urinary metabolites after consumption of specific foods

Lloyd

Favé

Beckmann

et al. 2011

The American Journal of Clinical Nutrition

119

125

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Background: The lack of robust biological markers of dietary exposure hinders the quantitative understanding of causal relations between diet and health. Objective: We aimed to develop an efficient procedure to discover metabolites in urine that may have future potential as biomarkers of acute exposure to foods of high public health importance. Design: Twenty-four participants were provided with a test breakfast in which the cereal component of a standardized breakfast was replaced by 1 of 4 foods of high public health importance; 1.5-, 3-, and 4.5-h postprandial urine samples were collected. Flow infusion electrospray-ionization mass spectrometry followed by supervised multivariate data analysis was used to discover signals resulting from consumption of each test food. Results: Fasted-state urine samples provided a universal comparator for food biomarker lead discovery in postprandial urine. The filtering of data features associated with consumption of the common components of the standardized breakfast improved discrimination models and readily identified metabolites that showed consumption of specific test foods. A combination of trimethylamine-N-oxide and 1-methylhistidine was associated with salmon consumption. Novel ascorbate derivatives were discovered in urine after consumption of either broccoli or raspberries. Sulphonated caffeic acid and sulphonated methyl-epicatechin concentrations increased dramatically after consumption of raspberries. Conclusions: This biomarker lead discovery strategy can identify urinary metabolites associated with acute exposure to individual foods. Future studies are required to validate the specificity and utility of potential biomarkers in an epidemiologic context. Am J Clin Nutr 2011;94:981-91.

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Section: Discussionmentioning

confidence: 99%

Use of mass spectrometry fingerprinting to identify urinary metabolites after consumption of specific foods

Lloyd

Favé

Beckmann

et al. 2011

The American Journal of Clinical Nutrition

119

125

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“…When comparing these data, we should however also consider the fact that the study by Gil-Agustì et al (2008) used minced meat containing only a certain percentage of the meat in question.…”

Section: Carnosine Anserine and Homocarnosinementioning

confidence: 99%

Determination of carnosine, anserine, homocarnosine, pentosidine and thiobarbituric acid reactive substances contents in meat from different animal species

et al. 2011

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The aim of this research was to determine the content of the histidinic antioxidants, advanced glycation end products (pentosidine) and thiobarbituric acid reactive substance (TBARS) in the meat from different animal species. Carnosine, anserine, homocarnosine and pentosidine were quantified by HPLC/MS, while TBARS was determined by photometric measurements. The total CRCs (carnosine+anserine+homocarnosine) content was in the increasing order: beef

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“…In the review reported by Song et al [6], they discuss the reaction mechanism of oxidative stress and certain chronic diseases, the relation between oxidative stress and inflammation, the effective reactive carbonyl species, the glycosylation end products sequestering actions of histidine-dipeptides and their metabolism, the effects of carnosinase encoding gene on the effectiveness of histidine-dipeptides and the protective effects of histidine-dipeptides against progression of metabolic syndrome in http detail. Anserine (L-histidine-b-alanyl-3-methyl) and carnosine (L-histidine-b-alanyl) are two histidine derivatives which are found in skeletal muscles, the heart and the central nervous system at very high concentrations [7][8][9]. Both are known to play some physiological roles in the muscle and brain.…”

Section: Introductionmentioning

confidence: 99%

A vibrational spectroscopy study on anserine and its aqueous solutions

Akkaya

Balci

Goren

et al. 2015

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Anserine and carnosine determination in meat samples by pure micellar liquid chromatography

Cited by 68 publications

References 20 publications

Use of mass spectrometry fingerprinting to identify urinary metabolites after consumption of specific foods

Use of mass spectrometry fingerprinting to identify urinary metabolites after consumption of specific foods

Determination of carnosine, anserine, homocarnosine, pentosidine and thiobarbituric acid reactive substances contents in meat from different animal species

A vibrational spectroscopy study on anserine and its aqueous solutions

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