Anodic voltammetric behaviors of methotrexate at a glassy carbon electrode and its determination in spiked human urine

Sensitive Voltammetric Sensor Based on Boron‐Doped Diamond Electrode for Determination of the Chemotherapeutic Drug Methotrexate in Pharmaceutical and Biological Samples

“…The methods using solid electrodes have also been reported for MTX determination. Gao a glassy carbon electrode (GCE) for study of the voltammetric behavior of MTX and the authors proposed its oxidation mechanism [31]. The authors reported that the amino group at the C2 position on the pyrimidine ring is electroactive and illustrated the possible mechanism of MTX oxidation which is shown in Figure 2 [31].…”

“…Gao a glassy carbon electrode (GCE) for study of the voltammetric behavior of MTX and the authors proposed its oxidation mechanism [31]. The authors reported that the amino group at the C2 position on the pyrimidine ring is electroactive and illustrated the possible mechanism of MTX oxidation which is shown in Figure 2 [31]. Other authors have utilized GCE with various surface modifications [32][33][34][35].…”

Determination of Methotrexate at a Silver Solid Amalgam Electrode by Differential Pulse Voltammetry

“…Wang et al 1986;El-Hady et al 2006;Gao et al 2007; F. Wang et al 2009;F. Wang et al 2012;Zhu et al 2013;Šelešovská, Janíková-Bandžuchová, and Chýlková 2014) and bismuth film electrodes (Asbahr et al 2013).…”

“…Wang et al 1986, Cataldi et al 1988, Ordieres et al 1990Ye et al 2005;Šelešovská, Bandžuchová, and Navrátil 2011), carbon based working electrodes (J. Wang et al 1986;El-Hady et al 2006;Gao et al 2007; F. Wang et al 2009;F. Wang et al 2012;Zhu et al 2013) and bismuth film electrode (Asbahr et al 2013), respectively, have been successfully applied for the voltammetric determination of this chemotherapeutic.…”

Electropolymerization of graphene and 5-[o-(4-bromine amyloxy) phenyl] -10,15,20-triphenylporphrin (o-BrPETPP) composite film electrode for the electrocatalytic oxidation of indirubin

“…Videlicet, it is necessary to develop an analytical assay for the determination of indirubin in complex matrices. In comparison with other potential methods, the electrochemical technique exhibits its predominance for the materials with electrochemical activity due to the advantages such as rapid response, low-cost and high sensitivity [6,7]. What's more, the electrochemical techniques also are helpful for identifying the redox properties of active materials and providing important information about pharmacological actions [8].…”