Annona reticulata Linn. (Bullock's heart): Plant profile, phytochemistry and pharmacological properties

Abstract

From the beginning of human civilization plants and plant based chemicals are the most important sources of medicines. Phytochemical and different products obtained from plant are used as medicines, pharmaceuticals, cosmetics and food supplements. Annona reticulata Linn. (牛心果 niú xīn guǒ; Bullock's heart) is a versatile tree and its fruits are edible. Parts of A. reticulata are used as source of medicine and also for industrial products. It possesses several medicinal properties such as anthelmintic, analgesic, anti-inflammatory, antipyretic, wound healing and cytotoxic effects. It is widely distributed with phytochemicals like tannins, alkaloids, phenols, glycosides, flavonoids and steroids. Present article is an attempt to highlight over taxonomy, morphology, geographical distribution, phytoconstituents and pharmacological activities of A. reticulata reported so far.

Antiallergic effect of the atomized extract of rhizome of <em>Curcuma longa</em>, flowers of <em>Cordia lutea</em> and leaves of <em>Annona muricata</em>

“…The other component, A. muricata , was originally used for its nutritional properties because it was an important source of various amino acids such as arginine, glutamine, and serine 21. However, it also showed antiparasitic effect,22 anti-infective activity against some strains of Staphylococcus , Pseudomonas , and Escherichia coli 23,24 and antioxidant and anti-inflammatory properties 18,25,26. The presence of nobiletin, a citrus flavonoid that is associated with the suppression of mast cell degranulation,27 could explain its effects 8…”

Chemical Constituents From the Seeds of Annona Reticulata L. In Vietnam

“…Leaf decoction is used for nervous shock, indigestion and abdominal pain [2] and leaf paste is applied externally for boils [3]. The phytochemical studies revealed that the plant contains acetogenins, alkaloids, diterpenoids, triterpenoids, phytosterols, phenolic compounds and flavonoids [4]. In the present study, we describe isolation and structural characterization of four compounds, including two triterpenoids, rotundic acid (1), pedunculoside (2), and two phenlic compounds eleutheroside B (3), sinapaldehyde glucoside (4).…”

In vitro evaluation of Anticancer Activity of Methnaolic Extract of Annona reticulata Linn. (Ramphal) Leaves on Different Human Cancer Cell Lines

“…Commonly known as custard apple is a traditionally important plant used for the treatment of various ailments. Traditionally plant is used for the treatment of dysentery, fever and as insecticide [5]. Different plant parts are effectively employed as folk medicine in the rural area of India.…”

“…The plant is rich in several phytochemicals such as dopamine, salsolinol, coclaurine, sesquiterpenes and acetogenin [6]. It also contains minerals such as Ca, P, K, Mg, Na, Cl, S, Mn, Zn, Fe, Cu, Se, Co, Ni and Cr [5]. In account with the medicinal properties of Annona reticulate Linn.…”