Ankyloblepharon Filiforme Congenitum Associated With Harelip and Cleft‐palate

Abstract

Ankyloblepharon filiforme congenitum (or adnatum) indicates a malformation in which the margins of the upper and lower eyelids are connected by extensile tissue bands. In the literature 24 cases have been reported.Lohlein (1930) showed a photograph of a baby with ankyloblepharon filiforme and an obvious cleft-lip. Later this coincidence of malformations have been reported by Khanna (1957) and by Long & Blandford (1962). V a n der W o u d e (1954) described a family with a strong occurrence of labial fistula, cleft-lip and cleft-palate, in which one of the patients with labial fistula had unilateral ankyloblepharon filiforme. The present case brings the number of the coincidence of ankyloblepharon and harelip and/or cleft-palate up to 5 out of a total of 24 cases of ankyloblepharon filiforme.A total ankyloblepharon in most cases occurs associated with severe facial and ocular malformations. Berndorfer (1965) in a report of four cases with gross defects of the facial structures presented one with complete cleft-lip and cleft-palate associated with homolateral, total ankyloblepharon and microphthalmos.

Cleft Lip With Ankyloblepharon Filiforme Adnatum: A Case Report

“…We found 7 cases of AFA associated with cleft lip and palate, as far as we could confirm (Table 1). [2][3][4][5][6][7][8] All of them were cases of cleft lip and palate. Additionally, there were no reports of cases with cleft lip only, such as the present case.…”

“…1 There are few reports of AFA with a cleft lip and palate. [2][3][4][5][6][7][8] There have been 55 reports of AFA in Japan and abroad, 9 and it is said that AFA often occurs alone. 10 However, congenital heart disease (patent ductus arteriosus and ventricular septal defect), 11 syndromes, such as syncytial finger 12 and imperforate anus, 13 18-trisomy, 11,14 and Hay-Well syndrome [15][16][17] have also been reported to present with AFA.…”