Ankyloblepharon Filiforme Adnatum

Abstract

Three infants had congenital eyelid bands, ankyloblepharon filiforme adnatum (AFA), in association with cleft lip and palate. A review of the literature of all previously reported cases of AFA was performed and a new classification of the various clinical types of AFA is proposed. This new classification should aid in genetic counseling.

Ankyloblepharon filiforme adnatum: a case report

“…Rosenman et al [7, 8] divide AFA into four subgroups (Table 1) and indicated that groups I and II were sporadic and groups III and IV were autosomal dominant with variable expressivity. Bacal et al [3] suggested a fifth group: AFA in association with chromosomal abnormalities.…”

Ankyloblepharon Filiforme Adnatum-A Rare Case

“…Systemic associations are seen4, which includes, Hay-Wells Syndrome (ankyloblepharon-ectodermal dysplasia-clefting syndrome), poplitealpterygium syndrome (characterised by webbing of knee), curly hairankyloblepharon-nail dysplasia syndrome, and cleft lip and palate. Rosenman et al [5] proposed a classification of AFA into four groups. Bacal et al [6] suggested a fifth group; AFA in association with chromosomal abnormalities.…”

Ankyloblepharon Filiforme Adnatum in a Newborn

“…Rosenman's 1980 classification divides AFA into four subgroups (1, isolated; 2, associated with cardiac or central nervous system anomalies; 3, associated with ectodermal syndromes; 4, associated with cleft lip and/or palate). 4 …”