Based on the crystal plasticity theory, the changes in TC4 titanium alloy before and after cutting, especially the changes in cutting forces, chip temperature, morphology, and quality, were analyzed in this study. Initially, a polycrystalline plasticity model for the TC4 titanium alloy was established. Following that, a crystal plasticity polycrystal finite element cutting simulation model is developed to perform cutting simulations. This model represents the mechanical behavior of the micro grains of TC4 titanium alloy during the deformation and cutting processes. Further, it validates the internal grain plastic deformation and the effect on the metallography of TC4 titanium alloy before and after cutting. The results show a good consistency between experimental and simulation data. The grain size increases gradually from the center to the edge of the cutting area, with the phenomenon of equiaxed grains becoming more apparent, leading to the formation of elongated fine grains. During the cutting process, grains interlock and fracture, exhibiting strong anisotropy.