Anisotrope Substanzen in Lymphknoten bei Sarkoidose

Mohri, Naotake

doi:10.1007/bf00432199

Cited by 4 publications

(5 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The compound nature of Schaumann bodies has been more fully described by Engle 15 and Williams. 6465 In 1974 Mohri 40 drew attention to small refractile bodies, 0.8-2 /xm by 3-7 itm, with a central dark isotropic "kern," also described by Johnson 27 in sarcoid and other granulomas as ring or notched forms. To be seen, frozen sections, or (for paraffin sections) short periods of fixation, avoidance of mineral acids, and PLM are needed.…”

Section: Discussionmentioning

confidence: 98%

“…Williams 64,65 found birefringent particles of all sizes in 41% and conchoid bodies in 35%, of 17 sarcoid tissues. Mohri 40 reported Schaumann bodies (defined as crystals in giant cells) in 22% of 50 sarcoid lymph nodes. Some indication of the frequency with which different crystal forms may coexist is given in Table 2.…”

Section: Prevalence and Coexistence Of Different Forms Of Oxalatementioning

confidence: 99%

“…Typical small ovoid bodies were found in lesions of tuberculosis and histoplasmosis and in nodes draining tumors, in general agreement with previous indications of nonspecificity of oxalate deposits. 40,64,65 Johnson and Pani 28 have proposed that oxalate is a secondary product of the inflammatory process.…”

Section: Disease Specificity and Role In Granuloma Formationmentioning

confidence: 99%

“…Birefringent crystalline material has long been recognized in giant cells and in the Schaumann bodies of sarcoidosis and has been variously thought to be calcite 4065 (one of the crystal forms of CaC0 3 ) or calcium oxalate. 27 (CaC 2 0 4 ) The small ovoid macrophage-related bodies, however, have been infrequently described, 27,40 and the objectives of this investigation were to establish their nature, prevalence, origin, specificity, and pathogenic significance, with the assistance of highly specialized microanalytic techniques and single particle analysis. When it was confirmed that the small bodies were composed of calcium oxalate (as indicated by Johnson 27 from histochemical examination), a few typical examples of the larger and better known birefringent particles of the sarcoid granulomas were also submitted to microanalytic examinations.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Calcium Oxalate in Sarcoid Granulomas: With Particular Reference to the Small Ovoid Body and a Note on the Finding of Dolomite

Reid

Andersen

1988

American Journal of Clinical Pathology

View full text Add to dashboard Cite

The nature, prevalence, and specificity of birefringent calcific particles in granulomas of sarcoidosis have been examined, including histochemical reactions, single particle, and microchemical analyses. Particular attention was paid to small ovoid forms of which most were calcium oxalate monohydrate. Larger crystals, those within giant cells, and the birefringent component of a Schaumann complex were also calcium oxalate. Small ovoids appeared to originate in macrophages and to be precursors of other forms; they were found in 86% of lymph nodes and 73% of surgical lung specimens. They were not specific for sarcoidosis. Organisms could not be certainly identified in them. Their origin is discussed in relation to activated macrophages, calcium, and oxalate metabolism, and the role of calcium oxalate in granulomas is considered. Four particles from two cases were dolomite and two were a calcium-sulphur compound. The biologic origin of dolomite is reviewed.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Prevalence and Coexistence Of Different Forms Of Oxalatementioning

confidence: 99%

Section: Disease Specificity and Role In Granuloma Formationmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Calcium Oxalate in Sarcoid Granulomas: With Particular Reference to the Small Ovoid Body and a Note on the Finding of Dolomite

Reid

Andersen

1988

American Journal of Clinical Pathology

View full text Add to dashboard Cite

show abstract

“…The evidence from the authors was that the formation of epithelioid granulomas, namely sarcoidosis, is based on the mechanism of hypersensitivity. In 1974, Mohri [7] discussed the connection of silicates and sarcoidosis as well.…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis after Adjustable Silicone Gastric Banding – a Report of Two Cases in Germany

et al. 2009

View full text Add to dashboard Cite

We report 2 patients who developed sarcoidosis after the implantation of adjustable silicone gastric banding (GB) in Germany. Before implantation, no pulmonary diseases were evident in the medical history of either patient. The 1st patient suffered sarcoidosis 12 months after GB. He has been treated at a hospital specialising in pulmonary diseases. Because of the treatment with corticoids, the patient has regained weight after the initial weight reduction. The 2nd patient developed signs of pulmonary infection on the 7th postoperative day (after GB). Pulmonary sarcoidosis was diagnosed 4 months later after consultation with a pulmonologist.

show abstract

Ultrastructural and histochemical investigations of spindle-shaped corpuscles in phagocytic cells of lymph nodes

Roggendorf

Groß

1977

Beiträge zur Pathologie

View full text Add to dashboard Cite

Anisotrope Substanzen in Lymphknoten bei Sarkoidose

Cited by 4 publications

References 8 publications

Calcium Oxalate in Sarcoid Granulomas: With Particular Reference to the Small Ovoid Body and a Note on the Finding of Dolomite

Calcium Oxalate in Sarcoid Granulomas: With Particular Reference to the Small Ovoid Body and a Note on the Finding of Dolomite

Sarcoidosis after Adjustable Silicone Gastric Banding – a Report of Two Cases in Germany

Ultrastructural and histochemical investigations of spindle-shaped corpuscles in phagocytic cells of lymph nodes

Contact Info

Product

Resources

About