Angka kejadian diabetes melitus pada pasien tuberkulosis

Novita, Emma; Ismah, Zata; Pariyana, Pariyana

doi:10.32539/jkk.v5i1.6122

Cited by 5 publications

(7 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The results of men aged >40 years old also became dominant in 2015 in Sebrang Ulu, Palembang 10 , while a study in India in 2018 reported that men aged >50 years old significantly increased the chances of morbidity of these two diseases. 11 These studies are relatable because older age is more vulnerable and the physiology of the patient's respiratory system is reduced, the barrier mechanism or microbial clearance can be damaged due to aging, 12 such as decreased ciliary function, pulmonary elasticity, and cough reflexes, which will increase the risk of infection with pulmonary TB 13 and added to T2DM disease can cause a decrease in cellular immune system, because blood sugar levels are always high and can reduce macrophage function.…”

Section: Discussionmentioning

confidence: 99%

“…11 These studies are relatable because older age is more vulnerable and the physiology of the patient's respiratory system is reduced, the barrier mechanism or microbial clearance can be damaged due to aging, 12 such as decreased ciliary function, pulmonary elasticity, and cough reflexes, which will increase the risk of infection with pulmonary TB 13 and added to T2DM disease can cause a decrease in cellular immune system, because blood sugar levels are always high and can reduce macrophage function. 10 In this study, the diagnosis of a patient's pulmonary TB was classified according to the treatment history, between new cases of TB or TB with a previous history, to make it easier to see rifampicin resistance. Gene Xpert TB/RIF has been recommended by WHO since 2010 and later in 2013 expanded its use as an initial diagnostic test in all people with signs and symptoms of TB.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Profile of Pulmonary Tuberculosis Patients with Type 2 Diabetes Mellitus in Pulmonary Department Dr. Soetomo General Hospital Surabaya

Soetrisno

Setiabudi

Wulandari

2020

View full text Add to dashboard Cite

Background: Pulmonary tuberculosis (TB) is the most important infectious disease, caused by Mycobacterium tuberculosis (MTB). Indonesia is the third country with the most prevalent TB cases in the world. Not all people who were exposed to MTB will become active TB, because the immune response is the main determinant. Immunocompromised person, such as patients who have type 2 diabetes mellitus (DM) as a comorbid are more prone to develop active TB infection. This study aimed to analyze the profile of pulmonary TB patients with type 2 DM in Pulmonary Department Dr. Soetomo General Hospital Surabaya.Methods: This was an observational descriptive study with a cross-sectional design. The research data were obtained from the medical records of TB patients with type 2 DM in Pulmonary Department Dr. Soetomo General Hospital Surabaya in January - December 2017.Results: Out of a total of 414 hospitalized patients, 74 patients with pulmonary TB were found with type 2 DM. Only 53 patients fulfilled the inclusion criteria. Gene Xpert results were sensitive (66.7%), previous TB treatment history (54.7%), unregulated type 2 DM (88.4%), RBG with the average of 311.83 mg/dl, PPBS with the average of 263.31 mg/dl, FBG with the average of 238 mg/dl, and HbA1C > 10% (68%).Conclusion: The majority of the patients of pulmonary TB with type 2 DM have average high blood glucose and unregulated DM.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Profile of Pulmonary Tuberculosis Patients with Type 2 Diabetes Mellitus in Pulmonary Department Dr. Soetomo General Hospital Surabaya

Soetrisno

Setiabudi

Wulandari

2020

View full text Add to dashboard Cite

show abstract

“…Efek DM terhadap perkembangan dan kesembuhan TB diperantai oleh adanya peradangan yang disebabkan oleh sitokin Interleukin 6, dan Tumor necrosis factor α sebagai respon terhadap infeksi TB menyebabkan peningkatan resistensi insulin sehingga menimbulkan hiperglikemia pada pasien dan penurunan produksi insulin dengan efek samping penggunaan isoniazid dan rifampisin yang dapat menimbulkan hiperglikemik, hal tersebut tentu menyulitkan proses kesembuhan dan keberhasilan pengobatan pasien TB-DM (6). Faktor-faktor yang dapat berpengaruh terhadap keberhasilan pengobatan TB-DM antara lain jenis kelamin, usia, kepemilikan jaminan kesehatan (JKN), pekerjaan, dan riwayat pengobatan sebelumnya (12). Tingkat kesembuhan yang rendah pada pasien TB-DM dapat dipengaruhi oleh usia yang relatif tua, tidak menjadi peserta JKN, konsumsi alkohol, merokok, dan adanya penyakit lain (5).…”

Section: Aunclassified

“…Strategi pengobatan bagi pasien TB-DM perlu dilakukan secara agresif untuk mencapai kadar gula yang optimal. 11 Kegagalan pengobatan pasien TB-DM berhubungan dengan beberapa faktor antara lain terjadinya resistensi OAT, kepatuhan pengobatan, adanya lesi paru yang luas, adanya gangguan imunitas tubuh dan penurunan konsentrasi obat (terutama rifampisin) (12).…”

Section: Aunclassified

Hubungan Antara Karakteristik Pasien dan Keberhasilan Pengobatan pada Pasien TB Paru dengan DM Tipe 2 di RSP Dr. H. A. Rotinsulu

Tegar Aria Yuda,

Heni Muflihah,

Miranti Kania Dewi

2024

BCSMS

View full text Add to dashboard Cite

Abstract. Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB). One factor that complicates treatment is the presence of comorbidities in pulmonary TB patients, including diabetes mellitus (DM). TB patients with diabetes mellitus comorbidities (TB-DM) are known to often experience treatment failure. This study aims to analyze the relationship between patient characteristics and treatment success in DM-TB patients. This study was a cross-sectional study. The study subjects were type 2 DM-TB patients at RSP Dr. H.A. Rotinsulu for the period 2022-2023. The data used is in the form of secondary data taken from the medical record of DM-TB patients at RSP Dr.H.A. Rotinsulu. The study sample was taken using purposive sampling totaling 130 people. Characteristics include age, gender, and ownership of the National Health Insurance (JKN). The final result of treatment after 6 months cured or complete is categorized as successful. The relationship of patient characteristics with treatment success was analyzed using the chi-square test. The results showed that most of the type 2 TB-DM patients at RSP Dr. H.A Rotinsulu were adults (19-60 years) as many as 84 people (71.8%), male as many as 72 people (61.5%), had JKN as many as 100 people (85.5%), and succeeded in treatment as many as 70 people (59.9%). There was a significant association between age and treatment success (p < 0.05), but no significant association between sex and JKN ownership and treatment success (p > 0.05). The conclusion of this study is that adulthood is associated with the success of DM-TB treatment. Productive age tends to have high motivation and healing spirit that can increase the success of treatment. Abstrak. Tuberkulosis (TB) merupakan penyakit infeksi menular yang disebabkan bakteri Mycobacterium tuberculosis (MTB). Salah satu faktor yang menyulitkan pengobatan adalah adanya penyakit penyerta pada pasien TB paru, diantaranya diabetes mellitus (DM). Pasien TB dengan penyakit penyerta diabetes mellitus (TB-DM) diketahui sering mengalami kegagalan pengobatan. Penelitian ini bertujuan untuk menganalisis hubungan antara karakteristik pasien dengan keberhasilan pengobatan pada pasien TB-DM. Penelitian ini merupakan studi cross sectional. Subjek penelitian adalah pasien TB-DM tipe 2 di RSP Dr. H.A. Rotinsulu periode 2022-2023. Data yang digunakan berupa data sekunder yang diambil dari rekam medik pasien TB-DM di RSP Dr.H.A. Rotinsulu.Sampel penelitian diambil menggunakan purposive sampling berjumlah 130 orang. Karakteristik meliputi usia, jenis kelamin, dan kepemilikan Jaminan Kesehatan Nasional (JKN). Hasil akhir pengobatan setelah 6 bulan sembuh atau lengkap dikategorikan berhasil. Hubungan karakteristik pasien dengan keberhasilan pengobatan dianalisis menggunakan chi-square test. Hasil penelitian menunjukkan sebagian besar pasien TB-DM tipe 2 di RSP Dr. H.A Rotinsulu berusia dewasa (19 – 60 tahun) sebanyak 84 orang (71.8%), berjenis kelamin laki-laki sebanyak 72 orang (61.5%), memiliki JKN sebanyak 100 orang (85.5%), dan berhasil dalam pengobatan sebanyak 70 orang (59.9%). Terdapat hubungan bermakna antara usia dan keberhasilan pengobatan (p < 0,05), namun tidak terdapat hubungan bermakna antara jenis kelamin dan kepemilikan JKN dengan keberhasilan pengobatan (p > 0,05). Simpulan penelitian ini adalah usia dewasa berhubungan dengan keberhasilan pengobatan TB-DM. Usia produktif cenderung memiliki motivasi dan semangat penyembuhan yang tinggi yang dapat meningkatkan keberhasilan pengobatan.

show abstract

“…Gangguan neuropati saraf autonom berupa hipoventilasi sentral dan sleep apneu. Perubahan lain yang juga terjadi yaitu penurunan elastisitas rekoil paru, penurunan kapasitas difusi karbonmonok-sida, dan peningkatan endogen produksi karbondioksida (11) .…”

Section: Pembahasanunclassified

Diabetes Mellitus dengan Status Gizi (Underweight) dalam Meningkatkan Resiko Kasus Tuberkulosis : Studi Kasus Kontrol di Puskesmas Mulyorejo

Marbun¹,

Widi²,

Dea³

2021

2-TRIK

View full text Add to dashboard Cite

The incidence and prevalence of tuberculosis (TB) and Diabetes Mellitus (DM) now is increasing rapidly in the world. The International Diabetes Federation reports that people with Diabetes Mellitus have a higher risk of developing tuberculosis. There are several risk factors that are thought to increase the incidence of tuberculosis, one of which is Diabetes Mellitus (DM). This study aims to determine the relations between DM and the incidence of TB at Puskesmas Mulyorejo Malang. The research design was case control. The sample consisted of 114 respondents covering 57 for the control group and 57 for the case group. Data analysis using logistic regression. In the tuberculosis group, the percentage of respondents with DM was 64.9%, while in the group who did not suffer from tuberculosis, the percentage of respondents with DM was 24.6%. In this study, DM interacted with nutritional status (underweight). Means, at the same smoking habit, the relationship between DM and TB incidence is different according to the nutritional status of the respondent. For the underweight respondents, DM has a 20.0 times higher chance of developing TB than respondents who do not have diabetes. For the future, the researchers who will conduct similar research can discusse more and also improve this research with broader research variables in form of correlation. Diabetes mellitus is a disease that can cause a decrease in the cellular immune system. Keywords: diabetes mellitus; tuberculosis ABSTRAK Insidensi dan prevalensi penyakit tuberkulosis (TB) dan Diabetes Mellitus (DM) meningkat cepat di dunia. International Diabetes Federation melaporkan penderita Diabetes Mellitus berisiko lebih tinggi untuk berkembang menjadi tuberkulosis. Terdapat beberapa faktor resiko yang diduga dapat meningkatkan kejadian Tuberkulosis, salah satunya adalah Diabetes Mellitus (DM) Penelitian ini bertujuan untuk mengetahui Hubungan antara DM dengan kejadian TB di Puskesmas Mulyorejo Malang. Desain penelitian adalah case control. Sampel berjumlah 114 responden yang meliputi 57 untuk kelompok kontrol dan 57 untuk kelompok kasus. Analisis Data menggunakan regresi logistik. Pada kelompok tuberkulsosis, presentase responden dengan DM sebesar 64,9%, sedangkan pada kelompok yang tidak menderita tuberkulosis, persentase responden dengan DM sebesar 24,6%. Pada penelitian ini, DM berinteraksi dengan status gizi (underweight). Artinya, pada kebiasaan merokok yang sama, hubungan DM dengan kejadian TB berbeda menurut status gizi responden. Pada responden yang underweight, DM memiliki peluang 20,0 kali lebih tinggi untuk terjadi TB dibandingkan responden yang tidak DM. Diabetes mellitus merupakan suatu penyakit yang dapat menyebabkan penurunan sistem imunitas selular. Kata kunci: diabetes melitus; tuberkulosis

show abstract

Angka kejadian diabetes melitus pada pasien tuberkulosis

Cited by 5 publications

References 2 publications

Profile of Pulmonary Tuberculosis Patients with Type 2 Diabetes Mellitus in Pulmonary Department Dr. Soetomo General Hospital Surabaya

Profile of Pulmonary Tuberculosis Patients with Type 2 Diabetes Mellitus in Pulmonary Department Dr. Soetomo General Hospital Surabaya

Hubungan Antara Karakteristik Pasien dan Keberhasilan Pengobatan pada Pasien TB Paru dengan DM Tipe 2 di RSP Dr. H. A. Rotinsulu

Diabetes Mellitus dengan Status Gizi (Underweight) dalam Meningkatkan Resiko Kasus Tuberkulosis : Studi Kasus Kontrol di Puskesmas Mulyorejo

Contact Info

Product

Resources

About