Angiosarcoma of the small intestine

Abstract

Primary gastrointestinal angiosarcomas are very rare and those of the small bowel even more rare. We report a case which is the first in the literature from this part of the world. It presented in a 25-year-old woman with multiple dissemination and rapid fatality. Diagnosis was based on histological morphology using Hematoxylin and Eosin (H and E) stains, plus reticulin special stain to outline the vascular nature.

Primary angiosarcoma of the small intestine with metastasis to the liver: a case report and review of the literature

“…Primary angiosarcoma of the small intestine is extremely rare; moreover, due to the difficulty of prompt and accurate diagnosis, its prognosis is very poor [1,4]. To the best of our knowledge, few cases of primary angiosarcoma of the small intestine have been reported in the English literature [5], especially primary angiosarcoma of the small intestine with metastasis to the liver in a young patient.…”

Angiosarcoma of small intestine presenting with intestinal obstruction

“…Symptoms include abdominal pain, nausea, vomiting, intestinal obstruction, anemia, gastrointestinal bleeding. 3,6 The pathogenesis is unclear; several etiologic factors have been suggested such as previous radiation, chronic lymphedema, exogenous toxins like thorotrast, vinyl chloride and arsenic, long-term peritoneal dialysis, intraabdominal foreign body, visceral metastasis from Kaposi's sarcoma and familial syndromes such as neurofibromatosis Type 1, mutated BRCA1 and BRCA2, Mafucci syndrome and Klippel-Trenaunay syndrome. 1,3,4 Magnetic resonance imaging (MRI), computerized tomography (CT), abdominal x-rays and ultrasound can be used for diagnosis but all of them have limited diagnostic utility.…”

Primary angiosarcoma of the small bowel: A case report

“…Magnetic resonance imaging (MRI) scan, computed tomography (CT) scan, abdominal X-rays and ultrasound can be used for diagnosis, but all of them have limited diagnostic utility [5,6].…”

“…Clinically, like other tumors of the small bowel, angiosarcomas have nonspecific symptoms including recurrent gastrointestinal bleeding, abdominal pain and nausea [2,[5][6][7]. The few cases described in the literature report rapid dissemination and very reserved prognosis with average survival from two to six months after diagnosis [3,6].…”