Angiomatous lymphoid‐tissue hyperplasia

Abstract

polyethylene glycol may be related to its known effect of potentiating the lytic action of complement on antibody-coated tumour cells in vitro, but other factors, such as the state of the reticulo-endothelial system, may also need to be taken into consideration. REFERENCES HARTVEIT, FLORA . PLATES LXIV AND LXV CASTLEMAN, I V E R S O N A N D M E N E N D E Z (1956) collected 13 benign tumour-like lesions of lymph-node origin localised in the mediastinum and published them under the designation " Localized mediastinal lymph-node hyperplasia resembling thymoma ". Harrison and Bernatz (1963) further qualified the above term as " angiofollicular mediastinal lymph-node hyperplasia ". In 1967 Tung and McCormack reviewed the hitherto published 45 intrathoracic and 17 extrathoracic cases and referred to them as "angiomatous lymphoid hamartoma ". Six reports of this condition have appeared in European literature (Zettergren, 1961 ; Pietra, 1964; Luthi, Sordat and Butler, 1966; Schumann, 1966; Cseh, 1967; Mobius and Schiitze, 1967). Despite the unknown aetiology and different designations, the characteristic and constant histological pattern clearly indicates a distinct entity.Basically a follicular and interfollicular proliferation of blood vessels coexists with a diffuse lymphoplasmocytic infiltration. The angiomatous lymphoid-tissue hyperplasia represents a clinical, roentgenological and histological problem.A further case is presented and aetiological considerations are discussed on the basis of the clinical and pathological features.

Cervical angiofollicular lymph node hyperplasia (lymphoid hamartoma)

“…The hyaline vascular type is often very vascular and bleeds readily during surgery. It seems to be related to the vascular proliferation seen microscopically (Castleman et al, 1956;Cheen, 1957;Krasznai and Juhasz, 1969;Mackay, 1969;Tung and McCormack, 1967). The term angiofollicular is coined because of the characteristic vascularity of the lesion.…”

Angiofollicular lymph node hyperplasia (Castleman)

“…Whether, in the light of Flendrig's separation of cases into two clinical and morphological groups, this will prove to be two diseases or one it is too early to say, but Krasznai and Juhasz (1969) describe a case cured of thrombopoenia whose lesion appears to correspond with the symptomless type. Certainly until more is known about this lesion it is wiser to document all cases together.…”

Unexpected Nature of a Pelvic Mass in Pregnancy: Castleman’s Disease

“…Castleman's disease has many synonyms in the litera ture, new terminology evolving with additional under standing of the condition and new hypotheses as to its etiology [7], Localized nodal hyperplasia [6], angioma tous lymph node hyperplasia [8], lymphoid hamartoma [9] and giant lymph node hyperplasia [10] are included, just to name a few. This disease has no predilection for age or sex [11], and usually presents as an asymptomatic mediastinal mass found on routine chest X-ray [6, 9, Two distinct histologic subtypes of Castleman's dis ease are identified: the hyaline vascular type and the plasma cell type [7], The plasma cell type comprises only 9% of total cases and is more likely to present with con stitutional symptoms [10], such as chronic refractory anemia, fever and hypergammaglobulinemia [10,13].…”