2008
DOI: 10.1186/1746-1596-3-22
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Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process

Abstract: Background: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a vasocentric process characterized by infiltrates of lymphocytes and eosinophils, usually affecting the muscular arteries of the head and neck. Currently it is unclear whether it is a reactive or neoplastic process.

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Cited by 40 publications
(36 citation statements)
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“…39 Several cases with histopathology of JTA have been reported in conjunction with systemic abnormalities, such as nephrotic syndrome, eosinophilia of 31% with multiarterial involvement (including bilateral temporal artery involvement), and history of lymphoma. 10,15,20 An additional case with isolated bilateral temporal artery involvement and no other manifestations has also been reported. 11 There has been only one reported case of a patient with a lesion histopathologically compatible with JTA and subsequent occurrence of an ALHE lesion without large vessel involvement.…”
Section: Discussionmentioning
confidence: 90%
See 1 more Smart Citation
“…39 Several cases with histopathology of JTA have been reported in conjunction with systemic abnormalities, such as nephrotic syndrome, eosinophilia of 31% with multiarterial involvement (including bilateral temporal artery involvement), and history of lymphoma. 10,15,20 An additional case with isolated bilateral temporal artery involvement and no other manifestations has also been reported. 11 There has been only one reported case of a patient with a lesion histopathologically compatible with JTA and subsequent occurrence of an ALHE lesion without large vessel involvement.…”
Section: Discussionmentioning
confidence: 90%
“…[15][16][17] Both diseases have J AM ACAD DERMATOL VOLUME 62, NUMBER 2 also been associated with the concurrent and or subsequent development of T-cell lymphoma; however, actual neoplastic evolution of the lymphocytic infiltrates in lesions of ALHE and Kimura disease has not been shown. [18][19][20][21][22][23][24][25] Although there have been several reports of both entities occurring in a single patient, 12,26,27 most authors view ALHE and Kimura disease as two distinct disorders. ALHE occurs in young to middleaged women, and presents with multiple small (\2 cm) erythematous dermal papules or nodules.…”
Section: Discussionmentioning
confidence: 99%
“…9 İlginç olarak, iki EAH raporunda birbirini izleyen ya da metasenkron olarak tanı, almış periferal T-hücre lenfoması olması, EAH'nin erken form bir lenfoma olabileceği sorusunu akla getirmiştir. 12,14 Ancak hastaların büyük çoğunluğunun benign karakterde olduğu vurgulanmaktadır. Olgumuz 13 yıl önce meme kanseri geçirmişti ve düzenli izlem altında idi.…”
Section: Discussionunclassified
“…ALHE affects patients 20-50 years old; it is rare in elderly and younger patients [1]. Although ALHE is generally considered an atypical and entirely benign reactive process, one report of a case that progressed to mycosis fungoides might lead to the interpretation of ALHE as an early form of T cell lymphoma [4].…”
Section: Discussionmentioning
confidence: 99%