Angiogenesis: from plants to blood vessels

Fan, Tai‐Ping; Yeh, Ju Ching; Leung, Ka Nang; Yue, Patrick Ying-Kit; Wong, Ricky N S

doi:10.1016/j.tips.2006.04.006

Cited by 206 publications

(153 citation statements)

References 65 publications

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“…The anti-angiogenic and anti-inflammatory effect of bioactive compounds found 433 commonly in foods and their role in the prevention and treatment of inflammatory 434 and angiogenic-associated pathogenesis has been previously reported [30]. There is no external funding associated with this study.…”

Section: Discussion 431 432mentioning

confidence: 92%

Date syrup–derived polyphenols attenuate angiogenic responses and exhibits anti-inflammatory activity mediated by vascular endothelial growth factor and cyclooxygenase-2 expression in endothelial cells

et al. 2016

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Section: Discussion 431 432mentioning

confidence: 92%

Date syrup–derived polyphenols attenuate angiogenic responses and exhibits anti-inflammatory activity mediated by vascular endothelial growth factor and cyclooxygenase-2 expression in endothelial cells

et al. 2016

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“…We performed an angiogenesis test in the group using PEMA-A polymer (powder form) due to the high tan δ values exhibited by this group. Several in vitro and in vivo method have been used to evaluate angiogenesis [8][9][10][11]26) . The various in vivo methods used include the Mile's assay, chicken embryo chorioallantoic membrane method, and the Matrigel subcutaneous implantation method; however, these methods have various limitations 26) .…”

Section: Discussionmentioning

confidence: 99%

“…It is possible to shorten the period of wound healing by promoting angiogenesis using various bioactive substances. Many researchers have reported that traditional Chinese drugs (crude drugs) have angiogenesis promoting effects, antimycotic properties, and antiangiogenic functions [8][9][10][11][12][13][14][15] . Yang et al 8) reported that several crude drugs such as Salvia miltiorrhiza Bunge (Danshen), Angelica sinensis (Danggui), Astragalus membranaceus Bunge (Huangqi), and Puerarin radix (Gegen) can promote angiogenesis by acting on proteins such as vascular endothelial growth factor (VEGF).…”

Section: Introductionmentioning

confidence: 99%

The effect of crude drugs on the angiogenic property and dynamic viscoelasticity of PEMA-based soft polymer materials

et al. 2017

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This study aimed to determine the effect of crude drugs on the dynamic viscoelasticity and angiogenic property of soft polymer materials, in vitro. Two kinds of polyethyl methacrylates, and crude drugs (Astragalus membranaceus Bunge [HQ] and Salvia miltiorrhiza Bunge [DS]) were used in their powdered forms. And, acetyl tributyl citrate and ethyl alcohol were used in the liquid form. The dynamic viscoelasticity of each specimen was measured after 0, 1, 3, 7, 14 and 28 days of immersion in distilled water. The CellPlayer angiogenesis PrimeKit assay was used to test angiogenesis. Significant differences in dynamic viscoelasticity were observed among the materials. Specimens containing 1 wt% HQ showed higher angiogenic activity than those containing 5 wt% and 10 wt% HQ, and DS. Our results suggest that the addition of low amounts of crude drugs to soft polymer materials may promote angiogenesis in human tissues.

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“…Because tumor growth and metastasis depend on tumor angiogenesis, inhibition of tumor angiogenesis is a novel therapeutic modality toward controlling tumor metastasis (Kruger et al, 2001). Angiogenesis is initiated by endothelial cell proliferation, migration, invasion and then tube formation (Fan et al, 2006). It has been shown that suppression at any step of the processes in angiogenesis will inhibit the formation of new blood vessels (Tournaire et al, 2004).…”

Section: Discussionmentioning

confidence: 99%