1987
DOI: 10.1016/0030-4220(87)90228-3
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Angina bullosa haemorrhagica: Clinical and laboratory features in 30 patients

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Cited by 50 publications
(61 citation statements)
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“…These data suggest that a lack of support to the small blood vessels in the areas surrounding HBA increases the chances of the development of bleeding in case of trauma. Direct immunofluorescence of the lesion is usually negative, although some authors have demonstrated the presence of inflammatory mediators such as complement component 3 (C3) and immunoglobulin G (IgG) (7)(8)(9)(10)(11).…”
Section: Discussionmentioning
confidence: 99%
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“…These data suggest that a lack of support to the small blood vessels in the areas surrounding HBA increases the chances of the development of bleeding in case of trauma. Direct immunofluorescence of the lesion is usually negative, although some authors have demonstrated the presence of inflammatory mediators such as complement component 3 (C3) and immunoglobulin G (IgG) (7)(8)(9)(10)(11).…”
Section: Discussionmentioning
confidence: 99%
“…HBA is not associated with skin lesions; the oral lesions are hemorrhagic, do not leave any residual scarring, and are not associated with desquamative gingivitis. In addition, findings of histopathological and immunofluorescence analysis are frequently unremarkable (3)(4)(5)(6)(7)(8)(9)(10). Furthermore, findings of blood tests (including hemogram, platelet count, and coagulation tests) are usually normal.…”
Section: Discussionmentioning
confidence: 99%
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“…7 Stephenson published a large series of 30 patients, not finding a clear precipitating factor in 47% of the cases.There have been many precipitating factors described: trauma by a sharp cusp or edge of an adjacent tooth or metal crown, masticatory trauma, hot drinks,use of steroids, as well as dental or injection of local anesthesia prior to extraction of teeth or vital crown preparation or root canal treatment. 8 One case of Angina Bullosa Hemmorhagica was reported in a 50 year old chronic renal failure Patient since two years who was on Hemodialysis for 8 months with Hypertension. 9 Differential diagnosis must include pemphigus, bullous pemphigoid, bullous lichen planus, dermatitis herpetiformis , Erythema Multiforme and thrombocytopenia.…”
Section: Discussionmentioning
confidence: 99%
“…The condition is known as angina bullosa haemorrhagica, a term first used by Badham in 1967 to describe oral blood blisters that could not be attributed to a blood dyscrasia, vesiculobullous disorder, or other known systemic disorder 2. Stephenson et al reviewed the laboratory features of the condition and concluded that, despite the presence of a subepithelial split histologically, there was no evidence of autoimmune mediated damage as with mucous membrane pemphigoid 3. Similarities between angina bullosa haemorrhagica and the acquired form of non-dystrophic epidermolysis bullosa have been suggested 4…”
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confidence: 99%