Anetoderma Secondary to Syphilis

Anetodermic lesions following pityriasis rosea and impetigo

“…6 Furthermore, very rare cases of anetoderma wich appeared after bacterial infections of the skin have been published: tuberculosis, 7,8 leprosy 7,9-11 and syphilis. 7,8,[12][13] In our patient, the medical history and clinical presentation of the lesions were consistent with the diagnosis of Pellizzari-Jadassohn anetoderma. We excluded familial, congenital and drug-induced anetoderma.…”

Acquired disorders of elastic tissue: Part II. decreased elastic tissue

“…23 Associated conditions. Secondary anetoderma has been associated with urticaria pigmentosa, 24 syphilis, 25 acne, 26 varicella, 27 Lyme disease, 28 leprosy, 29 HIV infection, 30,31 lymphoproliferative disorders, 32,33 Langerhans cell histiocytosis, 34 systemic lupus erythematosus, 14,35,36 primary hypothyroidism, 37 Graves disease, 38 Addison disease, 14 antiphospholipid syndrome, 39 Sjögren syndrome, 40 prurigo nodularis, 41 pilomatricoma, 42,43 application of leeches, 44 electrocardiographic lead placement, 45 hepatitis B vaccination, 46 chronic angular cheilitis, 47 congenital melanocytic nevi with hamartomatous features, 48 juvenile xanthogranuloma, 49 and generalized granuloma annulare. 50 Involvement of extracutaneous elastic tissue has not been reported.…”

Rosetoid schwannoma (neuroblastoma‐like) in association with an anetoderma

“…Secondary anetoderma occurs in association with another disease. Anetoderma is seen in association with inflammatory diseases including discoid and systemic lupus erythematous, antiphospholipid syndrome, acne, and cutaneous infections such as herpes zoster, borreliosis, 10 syphilis, 11 and human immunodeficiency virus 12 . It has also been described in association with skin tumors, including pilomatricomas 13,14 .…”