Rosetoid schwannoma (neuroblastoma‐like) in association with an anetoderma

Vélez, Dolores; Duran, Teresa Reina; Pérez‐Gala, S.; Fernandez, J. Fraga

doi:10.1111/j.1600-0560.2006.00480.x

Cited by 15 publications

(18 citation statements)

References 13 publications

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“…Velez et al . later suggested the terminology “rosettoid schwannoma”; however, this did not gain widespread acceptance …”

Section: Discussionmentioning

confidence: 91%

“…Neuroblastoma‐like schwannoma is one such rare variant of schwannoma, which mimics a malignant small round cell tumor (MSRCT) on histopathology. A comprehensive literature review identified only 19 cases of this entity reported to date (Table ) . We report the first case of this unusual tumor at the skull base, which caused a diagnostic dilemma…”

Section: Introductionmentioning

confidence: 91%

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Neuroblastoma‐like schwannoma of the skull base: an enigmatic peripheral nerve sheath tumor variant

et al. 2016

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Neuroblastoma-like schwannoma is an extremely rare histological variant of schwannoma, which histologically mimics a malignant small round cell tumor. Only 19 cases have been reported in the literature to date. We report a case of this tumor located at the skull base in a 44-year-old woman who presented with symptoms of right-sided earache and hearing loss. MRI revealed a large, lobulated, extra-axial mass measuring 8.8 cm × 3.6 cm × 4.2 cm in the floor of the middle and posterior cranial fossa. Microscopic examination revealed a perplexing histopathology with peculiar collagenous rosettes. Differential diagnoses included a broad range of benign and malignant tumors. Typical schwannoma seldom poses a difficulty in diagnosis; however, this unusual variant is a diagnostic challenge which requires an extensive clinico-radiological correlation and immunohistochemical work-up. Hence, knowledge of this entity is a must to avoid erroneous diagnosis and inappropriate treatment.

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“…Velez et al . later suggested the terminology “rosettoid schwannoma”; however, this did not gain widespread acceptance …”

Section: Discussionmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 91%

Neuroblastoma‐like schwannoma of the skull base: an enigmatic peripheral nerve sheath tumor variant

et al. 2016

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“…Since then, very few cases of this extremely uncommon but distinctive histological variant of benign schwannoma have been reported. [78] Skelton et al . in 1994 reported a case of a schwannoma with collagenous spherulosis.…”

Section: Discussionmentioning

confidence: 99%

“…[8] For example, ES may be confused with epithelial malignant peripheral nerve sheath tumor, myoepitheliomas, epithelioid fibromyxoid tumor of soft tissue, etc.,[2] and neuroblastoma-like schwannoma may be confused with neuroblastoma, fibromyxoid sarcoma, dendritic cell neurofibroma, etc. [4]…”

Section: Discussionmentioning

confidence: 99%

SkIndia Quiz 12: A firm yellowish nodule over lip

Gutte¹

2014

Indian Dermatol Online J

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“…Neuroblastoma‐like schwannoma was first described in 1994 by Goldblum et al in three patients 5 . To our knowledge, only 10 further cases of this rare entity have been reported in the literature so far 6–13 . In the present paper, we report two additional cases of neuroblastoma‐like schwannoma, one with a multinodular plexiform pattern, review the literature on this rare morphological variant and discuss its differential diagnosis.…”

mentioning

confidence: 54%

Cutaneous neuroblastoma‐like schwannoma: a report of two cases, one with a plexiform pattern, and a review of the literature

Suchak¹,

Luzar

Bacchi

et al. 2010

J Cutan Pathol

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Cutaneous schwannomas in their classical form are readily identified histologically. A number of variants, including ancient, cellular, epithelioid, plexiform, microcystic and neuroblastoma-like, may cause diagnostic difficulty and rarely be confused with malignancy. Neuroblastoma-like schwannoma was first described by Goldblum et al. in 1994, and very few cases have since been reported. It is a benign sporadic neoplasm with no reported association with neurofibromatosis, and is characterized histologically by small round lesional cells surrounding collagenous cores forming rosette-like structures. The differential diagnosis includes other lesions with the formation of rosettes including neuroblastoma, low-grade fibromyxoid sarcoma and dendritic cell neurofibroma, as well as primitive neuroectodermal tumors and rare malignant transformation in a schwannoma. We describe two further cases of this rare entity and review the literature on the subject. Our first case additionally has a plexiform multinodular pattern, a feature described in only one previous report.

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Rosetoid schwannoma (neuroblastoma‐like) in association with an anetoderma

Abstract: Because neither the histological pattern nor the type of tumor allows a differential diagnosis with neuroblastoma, we propose the descriptive term of rosetoid schwannoma. And to our knowledge, this will be the first case reported of rosetoid schwannoma associated to anetoderma.

Cited by 15 publications

References 13 publications

Neuroblastoma‐like schwannoma of the skull base: an enigmatic peripheral nerve sheath tumor variant

Neuroblastoma‐like schwannoma of the skull base: an enigmatic peripheral nerve sheath tumor variant

SkIndia Quiz 12: A firm yellowish nodule over lip

Cutaneous neuroblastoma‐like schwannoma: a report of two cases, one with a plexiform pattern, and a review of the literature

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