Anesthetic dependence of the inhibitory effect of neurotensin on pentagastrin-stimulated acid secretion in rats. A possible role for somatostatin

Hammer, Robert A.; Fernández, Ceneida; Ertan, Atilla; Arimura, Akira

doi:10.1016/0024-3205(91)90553-n

Cited by 6 publications

(1 citation statement)

References 13 publications

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“…Neurotensin is also located to nerve fibers of the enteric nervous system in the stomach, indicating that it may act as a local neuronal rather than an endocrine regulator. It has been proposed that neurotensin may induce the secretion of somatostatin and thereby exert its inhibitory action on acid secretion (53,414). Most recently, however, the low-affinity neurotenstin type 2 receptor (NTS 2 ) has been identified on the parietal cell, suggesting a direct influence.…”

Section: Other Substancesmentioning

confidence: 99%

Gastric Acid, Calcium Absorption, and Their Impact on Bone Health

Kopic

Geibel

2013

Physiological Reviews

133

106

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Calcium balance is essential for a multitude of physiological processes, ranging from cell signaling to maintenance of bone health. Adequate intestinal absorption of calcium is a major factor for maintaining systemic calcium homeostasis. Recent observations indicate that a reduction of gastric acidity may impair effective calcium uptake through the intestine. This article reviews the physiology of gastric acid secretion, intestinal calcium absorption, and their respective neuroendocrine regulation and explores the physiological basis of a potential link between these individual systems.

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Section: Other Substancesmentioning

confidence: 99%