Anesthésie des malades atteints de dystrophie musculaire progressive

Saint-Maurice, C; Egu, J.F.; Gaudiche, O; Loose, J. P.; Murat, I.

doi:10.1016/s0750-7658(89)80012-7

Cited by 5 publications

(2 citation statements)

References 48 publications

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“…These abnormalities lead to hypoventilation, impaired cough, and consequently atelectasis and respiratory failure [13]. In addition, there may be a ventilation-perfusion imbalance and a decrease in the response to CO2 with the appearance of hypoxia and hypercarbia [23]. The development of chronic respiratory insufficiency in DMD is a known finding, indicating increasing weakness of respiratory muscles, particularly loss of diaphragmatic strength.…”

Section: Discussionmentioning

confidence: 99%

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Preoperative considerations and recommendations for anesthetic management in patients with Duchenne dystrophy disorders

Delgado¹,

Ferreira²,

Oliveira³

et al. 2022

Med Clin Sci

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Duchenne muscular dystrophy (DMD) is caused by the lack of functional dystrophin protein. Improvements in patient care and disease management may increase the quality of life, but currently, there is no treatment to stop the relentless loss of muscle tissue and function. This condition is associated with life-threatening perioperative complications including heart failure, respiratory insufficiency, rhabdomyolysis, and hyperkalemia. We reviewed the relevant literature about the preoperative evaluation and the safer anesthetic techniques used in patients with DMD. This article presents a short review of the anesthetic procedures to be followed in patients with DMD.

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Section: Discussionmentioning

confidence: 99%

“…Patients with a vital capacity of less than 30%, forced expiratory volume of less than 25%, and maximal voluntary ventilation of less than 50% will normally require prolonged postoperative mechanical ventilation [13,23].…”

Section: Discussionmentioning

confidence: 99%