Association propofol-alfentanil pour chirurgie cornéenne chez un patient atteint d'une maladie de Duchenne de Boulogne

A tie for the larngeal mask airway

“…Ginsburg et al have reported previously the use of a propofol infusion in the anaesthetic management of a 10-year-old patient with Duchenne muscular dystrophy [3], anaesthesia being maintained with infusion rates of 6-9 mg.kg-'.h-' in a paralysed patient. Juhel et al describe the use of a propofol infusion in a 17-year-old patient with Duchenne muscular dystrophy using an infusion rat0 of 10 mg.kg-'.h-' [4]. Again the infusion rates used in both these cases are decidedly lower than the infusion rates reported here.…”

Cardiac Arrest during Major Spinal Scoliosis Surgery in a Patient with Duchenne's Muscular Dystrophy Undergoing Intravenous Anaesthesia

“…Propofol is not thought to be a trigger agent for MH and its safe use has been reported previously in the anaesthetic management of DMD 6 . 7 • We used a pharmacokinetic model driven computer-controlled device to produce a slow, controlled induction of anaesthesia followed by blood levels easily adaptable to the patient's varying needs with fast recovery. The predicted plasma propofollevels required in our patient varied from 1 to 5 p.g/ml at different stages of the procedure and the total propofol consumption over eight hours was 1,5lO mg with supplementation from nitrous oxide (70070 in oxygen) and alfentanil (total dose 19 mg).…”