Anelloviruses

Segalés, Joaquím; Kekarainen, Tuija

doi:10.1002/9781119350927.ch26

Cited by 3 publications

(2 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Samples from the states of Odisha and Kerala were negative for TTSuV1, while those from Andhra Pradesh, Arunachal Pradesh, Sikkim, and Punjab were negative in both the genus-specific PCRs. Considering the variable prevalence (17-100%) of TTSuVs globally [6], screening of a larger number of samples from the above states would be required to accurately assess their prevalence in these regions. It is worth noting that although TTSuVs have been detected in different organs, relatively high detection rates have been found in the kidneys of apparently healthy slaughterhouse aged pigs [21].…”

Section: Discussionmentioning

confidence: 99%

“…At present, no clinical signs are specifically associated with TTSuV infection, and no clinicopathological experimental studies involving conventional pigs have been done due to the lack of readily available isolates [6]. However, there is a report that inoculation of gnotobiotic pigs with TTSuV1-containing tissue homogenate caused mild interstitial pneumonia, transient thymic atrophy, membranous glomerulonephropathy, and modest lymphocytic-to-histiocytic liver infiltrates [7].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Detection of torque teno sus virus infection in Indian pigs

et al. 2019

View full text Add to dashboard Cite

Background and Aim: Torque teno viruses (TTVs) are circular, single-stranded DNA viruses, which infect a wide range of animals including livestock and companion animals. Swine TTVs (torque teno sus viruses [TTSuVs]) are thought to act as a primary or coinfecting pathogen in pathological conditions such as porcine dermatitis and nephropathy syndrome and post-weaning multisystemic wasting syndrome. So far, the presence of the virus has not been reported in India. Considering that TTSuVs have the potential to cross the species barrier into humans and that pork consumption is common in North-Eastern states of India, the current study aims to investigate the presence of TTSuV in the Indian pig population. Materials and Methods: A total of 416 samples were collected during 2014-2018, from both apparently healthy pigs and also from pigs suspected of having died from classical swine fever and/or porcine reproductive and respiratory syndrome. These samples were screened for TTSuV infection by polymerase chain reaction (PCR) and DNA sequencing techniques. Results: The presence of the virus was confirmed in 110 samples from 12 different states of India. Phylogenetic analysis of the nucleotide sequences obtained from the PCR products indicated the presence of viruses of both Iotatorquevirus and Kappatorquevirus genera in India. Conclusion: The study is the first report on the presence of TTSuVs in India and highlights the circulation of both genera of the virus in the country.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Detection of torque teno sus virus infection in Indian pigs

et al. 2019

View full text Add to dashboard Cite

show abstract

Viral metagenomics reveals two novel anelloviruses in feces of experimental rats

Ning

Zhou

Yang

et al. 2021

Virol J

View full text Add to dashboard Cite

Background Rodents are widely distributed and are the natural reservoirs of a diverse group of zoonotic viruses. Thus, analyzing the viral diversity harbored by rodents could assist efforts to predict and reduce the risk of future emergence of zoonotic viral diseases. Rodents are commonly used in animal testing, particularly mice and rats. Experimental rats are important animal models, and a history of pathogenic infections in these animals will directly affect the animal trial results. The pathogenicity of Anellovirus (AV) remains poorly understood due to the lack of a suitable model cell line or animal to support the viral cycle. This study aimed to discover possible anelloviruses from the virome in feces of experimental rats by viral metagenomic technique. Methods Fecal samples were collected from 10 commercial SD rats and pooled into a sample pool and then subjected to libraries construction which was then sequenced on Illumina MiSeq platform. The sequenced reads were analyzed using viral metagenomic analysis pipeline and two novel anelloviruses (AVs) were identified from fecal sample of experimental rats. The prevalence of these two viruses was investigated by conventional PCR. Results The complete genomic sequence of these two AVs were determined and fully characterized, with strain name ratane153-zj1 and ratane153-zj2. The circular genomes of ratane153-zj1 and ratane153-zj2 are 2785 nt and 1930 nt in length, respectively, and both include three ORFs. Ratane153-zj1 closely clustered with members within the genus Wawtorquevirus and formed a separate branch based on the phylogenetic tree constructed over the amino acid sequence of ORF1 of the two AVs identified in this study and other related AVs. While the complete amino acid sequences of ORF1 of ratane153-zj2 (nt 335 to 1390) had the highest sequence identity with an unclassified AV (GenBank No. ATY37438) from Chinchilla lanigera, and they clustered with one AV (GenBank No. QYD02305) belonging to the genus Etatorquevirus from Lynx rufus. Conventional PCR with two sets of specific primers designed based on the two genomes, respectively, showed that they were detectable at a low frequency in cohorts of experimental rats. Conclusion Our study expanded the genome diversity of AVs and provided genetic background information of viruses existed in experimental rats.

show abstract

A Review on Pathological and Diagnostic Aspects of Emerging Viruses—Senecavirus A, Torque teno sus virus and Linda Virus—In Swine

Hawko

Burrai

Polinas

et al. 2022

Veterinary Sciences

View full text Add to dashboard Cite

Swine production represents a significant component in agricultural economies as it occupies over 30% of global meat demand. Infectious diseases could constrain the swine health and productivity of the global swine industry. In particular, emerging swine viral diseases are omnipresent in swine populations, but the limited knowledge of the pathogenesis and the scarce information related to associated lesions restrict the development of data-based control strategies aimed to reduce the potentially great impact on the swine industry. In this paper, we reviewed and summarized the main pathological findings related to emerging viruses, such as Senecavirus A, Torque teno sus virus, and Linda virus, suggesting a call for further multidisciplinary studies aimed to fill this lack of knowledge and better clarify the potential role of those viral diseases in swine pathology.

show abstract

Anelloviruses

Cited by 3 publications

References 50 publications

Detection of torque teno sus virus infection in Indian pigs

Detection of torque teno sus virus infection in Indian pigs

Viral metagenomics reveals two novel anelloviruses in feces of experimental rats

A Review on Pathological and Diagnostic Aspects of Emerging Viruses—Senecavirus A, Torque teno sus virus and Linda Virus—In Swine

Contact Info

Product

Resources

About