Detection of torque teno sus virus infection in Indian pigs

Subramanyam, Vinutha; Hemadri, D.; Kashyap, Shashidhara Phani; Hiremath, Jagadish; Barman, Nagendra Nath; Ralte, Esther Lalzoliani; Patil, S. S.; Suresh, Kuralayanapalya Puttahonnappa; Rahaman, Habibur

doi:10.14202/vetworld.2019.1467-1471

Cited by 3 publications

(2 citation statements)

References 24 publications

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“…Torque teno sus virus was another virus found in serum, but also in this case, no association with the severity could be established. TTSuV is found all over the world [ 26 , 27 ] there is no clear link between the virus and any clinical signs [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Porcine ear necrosis: characterization of lesions and associated pathogens

Malik,

Chiers,

Theuns

et al. 2023

Vet Res

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Porcine ear necrosis (PEN) is characterized by ulcerative lesions of the ear auricle. To investigate that problem, three farms with PEN in nursery pigs were included, and the study aim was to characterize PEN and the potential role of pathogens and mycotoxins. Within each farm, one batch of weaned piglets was included and the prevalence and severity of PEN were monitored for 6–7 weeks. Within each batch, 30 PEN-affected/non-affected animals were randomly selected. Blood samples were taken from these animals, to assess the systemic presence of pathogens and mycotoxins, as well as punch biopsies from the ear auricle for histopathological examination. From 10 animals, scrapings and swabs from the lesions were subjected to nanopore metagenomic sequencing and bacteriological cultivation, respectively. In all three farms, lesions appeared within 3–4 weeks post-weaning. The prevalence at the end of the nursery was 33%, 24%, and 46% for farms A, B, and C, respectively. Most affected pigs had mild to moderate lesions. Blood samples revealed low to very low levels of pathogens and mycotoxins. Different bacteria such as Staphylococcus, Streptococcus, Fusobacterium, Mycoplasma, and Clostridium species were identified by sequencing in the scrapings. The first two pathogens were also most often identified in bacterial cultures. Mycoplasma hyopharyngis was only found in PEN-affected pigs. Histopathological changes were primarily observed in the outer layer of the epidermis. The results suggest that PEN lesions develop by damage to the outer part of the skin e.g. by ear suckling or biting, followed by multiplication of opportunistic pathogens.

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Section: Discussionmentioning

confidence: 99%

Porcine ear necrosis: characterization of lesions and associated pathogens

Malik,

Chiers,

Theuns

et al. 2023

Vet Res

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“…In general, TTSuV seroprevalence and/or detection of viral DNA seems to be high in various regions in the Americas, Asia and Europe such as the USA, Canada, Uruguay, Brazil, China, India, Thailand, Korea, Italy and Spain [ 15 , 16 , 17 , 18 , 19 ]. In Table S1 , an overview of the detection and prevalence of TTSuV in several European countries is given [ 15 , 17 , 20 , 21 , 22 , 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

First Report of TTSuV1 in Domestic Swiss Pigs

Polster

Lechmann

Lienhard

et al. 2022

Viruses

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Serum prevalence of Torque teno sus viruses (TTSuV1 and k2; family Anelloviridae) is known to be high in the porcine population worldwide but pathogenesis and associated pathomorphological lesions remain to be elucidated. In this study, quantitative real-time PCR for detection of TTSuV1 was performed in 101 porcine samples of brain tissue, with animals showing inflammatory lesions or no histological changes. Additionally, a pathomorphological and immunohistochemical characterization of possible lesions was carried out. Selected cases were screened by TTSuV1 in situ hybridization. Furthermore, TTSuV1 quantitative real-time PCR in splenic and pulmonary tissue and in situ hybridization (ISH) in spleen, lungs, mesenteric lymph node, heart, kidney, and liver were performed in 22 animals. TTSuV1 was detected by PCR not only in spleen and lung but also in brain tissue (71.3%); however, in general, spleen and lung tissue displayed lower Ct values than the brain. Positive TTSuV1 results were frequently associated with the morphological diagnosis of non-suppurative encephalitis. Single TTSuV1-positive lymphocytes were detected by ISH in the brain but also in lungs, spleen, mesenteric lymph node and in two cases of non-suppurative myocarditis. A pathogenetic role of a TTSuV1 infection as a co-factor for non-suppurative encephalitides cannot be ruled out.

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A Review on Pathological and Diagnostic Aspects of Emerging Viruses—Senecavirus A, Torque teno sus virus and Linda Virus—In Swine

Hawko

Burrai

Polinas

et al. 2022

Veterinary Sciences

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Swine production represents a significant component in agricultural economies as it occupies over 30% of global meat demand. Infectious diseases could constrain the swine health and productivity of the global swine industry. In particular, emerging swine viral diseases are omnipresent in swine populations, but the limited knowledge of the pathogenesis and the scarce information related to associated lesions restrict the development of data-based control strategies aimed to reduce the potentially great impact on the swine industry. In this paper, we reviewed and summarized the main pathological findings related to emerging viruses, such as Senecavirus A, Torque teno sus virus, and Linda virus, suggesting a call for further multidisciplinary studies aimed to fill this lack of knowledge and better clarify the potential role of those viral diseases in swine pathology.

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Detection of torque teno sus virus infection in Indian pigs

Cited by 3 publications

References 24 publications

Porcine ear necrosis: characterization of lesions and associated pathogens

Porcine ear necrosis: characterization of lesions and associated pathogens

First Report of TTSuV1 in Domestic Swiss Pigs

A Review on Pathological and Diagnostic Aspects of Emerging Viruses—Senecavirus A, Torque teno sus virus and Linda Virus—In Swine

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