Androgenetic alopecia in adolescents: A report of 43 cases

Kim, Beom Joon; Kim, Ji Young; Eun, Hee Chul; Kwon, Oh Sang; Kim, Myeung Nam; Ro, Byung In

doi:10.1111/j.1346-8138.2006.00161.x

Cited by 37 publications

(45 citation statements)

References 17 publications

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“…23,24 This condition and overactive oil glands have been demonstrated to be a major factor in hair loss. 25 Whether the cessation of the hair loss is a result of ligation of the vessels or inadvertent injury of the accompanying nerves is not clear and will need additional investigation. We believe that our findings may offer a significant opportunity in the treatment of hairline recession and perhaps loss.…”

Section: Discussionmentioning

confidence: 99%

Cessation of Hairline Recession following Open Forehead Rejuvenation

Guyuron

Kriegler²,

Davis³

et al. 2014

Plastic and Reconstructive Surgery

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The purpose of this study was to investigate the efficacy of surgical deactivation of migraine headache trigger sites. Of 125 patients diagnosed with migraine headaches, 100 were randomly assigned to the treatment group and 25 served as controls, with 4:1 allocation. Patients in the treatment group were injected with botulinum toxin A for identification of trigger sites. Eighty-nine patients who noted improvement in their migraine headaches for 4 weeks underwent surgery. Eighty-two of the 89 patients (92 percent) in the treatment group who completed the study demonstrated at least 50 percent reduction in migraine headache frequency, duration, or intensity compared with the baseline data; 31 (35 percent) reported elimination and 51 (57 percent) experienced improvement over a mean follow-up period of 396 days. In comparison, three of 19 control patients (15.8 percent) recorded reduction in migraine headaches during the 1-year follow-up (p < 0.001), and no patients observed elimination. All variables for the treatment group improved significantly when compared with the baseline data and the control group, including the Migraine-Specific Questionnaire, the Migraine Disability Assessment score, and the Short Form-36 Health Survey. The mean annualized cost of migraine care for the treatment group (925 dollars) was reduced significantly compared with the baseline expense (7612 dollars) and the control group (5530 dollars) (p < 0.001). The mean monthly number of days lost from work for the treatment group (1.2) was reduced significantly compared with the baseline data (4.41) and the control group (4.4) (p = 0.003). The common adverse effects related to injection of botulinum toxin A included discomfort at the injection site in 27 patients after 227 injections (12 percent), temple hollowing in 19 of 82 patients (23 percent), neck weakness in 15 of 55 patients (27 percent), and eyelid ptosis in nine patients (10 percent). The common complications of surgical treatment were temporary dryness of the nose in 12 of 62 patients who underwent septum and turbinate surgery (19.4 percent), rhinorrhea in 11 (17.7 percent), intense scalp itching in seven of 80 patients who underwent forehead surgery (8.8 percent), and minor hair loss in five (6.3 percent). Surgical deactivation of migraine trigger sites can eliminate or significantly reduce migraine symptoms. Additional studies are necessary to clarify the mechanism of action and to determine the long-term results.

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Section: Discussionmentioning

confidence: 99%

Cessation of Hairline Recession following Open Forehead Rejuvenation

Guyuron

Kriegler²,

Davis³

et al. 2014

Plastic and Reconstructive Surgery

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“…[32,36,41] In contrast, seven females of the total 43 adolescent cases had AGA in an another study from Korea. [42] Interestingly, 20% of males with AGA had a "female pattern." In the majority of patients with AGA, the T and DHEA-S serum levels fell within the normal range.…”

Section: Female Pattern Hair Loss In Adolescents Female Pattern Hair mentioning

confidence: 99%

“…A family history of AGA in one/both parents or first-degree relatives is more common in patients who develop alopecia before adolescence than during adulthood (30.9-64.5%). [5,[41][42][43] …”

Section: Female Pattern Hair Loss In Adolescents Female Pattern Hair mentioning

confidence: 99%

Female pattern hair loss

Singal

Sonthalia

Verma

2013

Indian J Dermatol Venereol Leprol

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Female pattern hair loss (FPHL) is a common cause of hair loss in women characterized by diffuse reduction in hair density over the crown and frontal scalp with retention of the frontal hairline. Its prevalence increases with advancing age and is associated with significant psychological morbidity. The pathophysiology of FPHL is still not completely understood and seems to be multifactorial. Although androgens have been implicated, the involvement of androgen-independent mechanisms is evident from frequent lack of clinical or biochemical markers of hyperandrogenism in affected women. The role of genetic polymorphisms involving the androgen and estrogen receptors is being increasingly recognized in its causation and predicting treatment response to anti-androgens. There are different clinical patterns and classifications of FPHL, knowledge of which facilitates patient management and research. Chronic telogen effluvium remains as the most important differential diagnosis. Thorough history, clinical examination, and evaluation are essential to confirm diagnosis. Patients with clinical signs of androgen excess require assessment of biochemical parameters and imaging studies. It is prudent to screen the patients for metabolic syndrome and cardiovascular risk factors. The treatment comprises medical and/or surgical modalities. Medical treatment should be initiated early as it effectively arrests hair loss progression rather than stimulating regrowth. Minoxidil continues to be the first line therapy whereas anti-androgens form the second line of treatment. The progressive nature of FPHL mandates long-term treatment for sustained effect. Medical therapy may be supplemented with cosmetic concealment in those desirous of greater hair density. Surgery may be worthwhile in some carefully selected patients.

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“…Although AGA is more frequent in adults, it can also appear in adolescents , though its prevalence among this younger population is not well established [12,13]. On an average, adolescent AGA onset starts after puberty between 13.5 and 15 years of age [14].…”

Section: Introductionmentioning

confidence: 99%

Androgenetic Alopecia: a Review and Emerging Treatments

Alves¹

2017

CRDOA

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Androgenetic Alopecia (AGA) is the most common noncicatricial alopecia that leads to the progressive miniaturization of the hair follicle. Scalp terminal hairs are converted into vellus hairs, primarily due to two factors: genetic predisposition and hormonal stimulation.The incidence and prevalence of AGA increases with age. The onset of AGA is gradual, and when this pathology progresses, the anagen phase shortens and the telogen phase remains constant. The shedding area varies from patient to patient and is usually most marked at the vertex in men, while women with AGA generally lose hair diffusely over the crown.Topical minoxidil and oral finasteride (5-alpha-reductase type II inhibitor) are the gold-standard therapies for AGA and are currently the only Food and Drug Administration (FDA)-approved drugs for the treatment of AGA.The currently available treatments for AGA are sometimes perceived as having limited effectiveness; therefore, the identification of new therapies for this pathology is of utmost importance.This article aims to review the pathogenesis, diagnosis of AGA and all the new emerging treatments for this entity in order to prevent its progression and improve the results of this pathology.

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Androgenetic alopecia in adolescents: A report of 43 cases

Cited by 37 publications

References 17 publications

Cessation of Hairline Recession following Open Forehead Rejuvenation

Cessation of Hairline Recession following Open Forehead Rejuvenation

Female pattern hair loss

Androgenetic Alopecia: a Review and Emerging Treatments

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