2021
DOI: 10.3390/brainsci11020239
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Androgen Affects the Inhibitory Avoidance Memory by Primarily Acting on Androgen Receptor in the Brain in Adolescent Male Rats

Abstract: Adolescence is the critical postnatal stage for the action of androgen in multiple brain regions. Androgens can regulate the learning/memory functions in the brain. It is known that the inhibitory avoidance test can evaluate emotional memory and is believed to be dependent largely on the amygdala and hippocampus. However, the effects of androgen on inhibitory avoidance memory have never been reported in adolescent male rats. In the present study, the effects of androgen on inhibitory avoidance memory and on an… Show more

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Cited by 5 publications
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“…Orchiectomized rats spent significantly less time in the illuminated box after foot-shock training and had reduced AR-immunoreactivity in amygdala/hippocampal CA1 region in comparison to sham-operated males. The treatment of these male rats with both T and DHT reversed these effects which suggest that androgens enhance inhibitory avoidance memory probably by binding to AR ( Islam et al, 2021 ).…”
Section: Androgens and Estrogensmentioning
confidence: 87%
“…Orchiectomized rats spent significantly less time in the illuminated box after foot-shock training and had reduced AR-immunoreactivity in amygdala/hippocampal CA1 region in comparison to sham-operated males. The treatment of these male rats with both T and DHT reversed these effects which suggest that androgens enhance inhibitory avoidance memory probably by binding to AR ( Islam et al, 2021 ).…”
Section: Androgens and Estrogensmentioning
confidence: 87%