Ancient Schwannoma

Canella, Clarissa; Costa, Fernando José Pereira da; Klumb, Evandro Mendes; Aymoré, Ierecê Lins; Marchiori, Edson

doi:10.1002/art.37983

Cited by 5 publications

(5 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One of the infrequent variations of schwannomas is the ancient schwannoma, which was initially documented by Ackerman and Taylor in 1951 (12). These tumors account for just 0.8% of all soft tissue neoplasms (13). Ancient schwannomas display distinctive degenerative features, including cystic changes, fibrosis, stromal edema, xanthomatous alterations and perivascular hyalinization.…”

Section: Discussionmentioning

confidence: 99%

Degenerated (Ancient) Schwannomas: Unraveling Unusual Locations and Treatment Management

Gunerhan,

Çağıl,

Senol

et al. 2024

Genel Tıp Dergisi

View full text Add to dashboard Cite

Background/Aims: Schwannomas, originating from Schwann cells in peripheral nerve sheaths, exhibit diverse clinical manifestations and unpredictable behavior. Among them, ancient schwannomas, with distinctive degenerative features, present in atypical locations and pose diagnostic challenges. This study explores their unique characteristics and implications for diagnosis and management. Material and Methods: The study was designed as a retrospective analysis of 7 adult patients aged ≥18 years, diagnosed with paraspinal, presacral, sacral, or para-aortic tumors, all confirmed histologically as ancient schwannomas. Data for analysis were collected from patients treated and followed up at Ankara City Hospital between April 2017 and December 2022. Ethical approval and informed consent were obtained before inclusion in the study. Results: The most common symptoms included the presence of a local lump (71,4%) and localized or radiating pain (57,1%). Notably, 1 patient (14,2%) was incidentally diagnosed during the evaluation process. Surgical intervention played a crucial role in the management of these tumors, with 71,4% of patients undergoing complete resection, while 28,5% underwent subtotal resection. Tumor recurrence occurred in 42,8% of cases, prompting the administration of radiotherapy as part of the treatment strategy. Imaging findings, particularly on MRI, played a crucial role in the accurate identification of ancient schwannomas. These tumors displayed isointensity on T1-weighted images and heterogeneous hyperintensity on T2-weighted images, along with distinctive heterogeneous contrast enhancement. Conclusion: Ancient schwannomas exhibit unique histological features and distinctive MRI characteristics, differentiating them from other nerve sheath tumors. Early diagnosis and complete surgical resection offer favorable outcomes. Awareness of this entity is essential for managing peripheral nerve sheath tumors effectively.

show abstract

Section: Discussionmentioning

confidence: 99%

Degenerated (Ancient) Schwannomas: Unraveling Unusual Locations and Treatment Management

Gunerhan,

Çağıl,

Senol

et al. 2024

Genel Tıp Dergisi

View full text Add to dashboard Cite

show abstract

“… 13 The histologic analysis is characterized by interstitial hyalinization, degenerative atypia, and cells with large and hyperchromatic nuclei. 14 …”

Section: Discussionmentioning

confidence: 99%

Ancient Schwannoma of superficial peroneal nerve presenting as intermittent leg pain: A case report

Nascimento¹,

Nomi²,

Marques³

et al. 2015

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

INTRODUCTIONSchwannomas are benign, encapsulated, slow-growing and usually solitary tumors originating from Schwann cells of the peripheral nerve sheath. Schwannomas of the superficial peroneal nerves are very rare, and therefore scarcely documented in the literature. The authors report a case of a diagnosed superficial fibular nerve sheath tumor with an unreported clinical presentation.PRESENTATION OF CASEA 52-year-old Caucasian female arrived to our Orthopedics Department complaining of pain and numbness of the lateral aspect of her left leg. These symptoms were present for a year and were more evident at the end of the day, or after a long time in the orthostatic position. No evidence of other medical illnesses was found. There was no record of prior traumatic events related to that limb. Diagnosis of a benign peripheral nerve tumor was achieved and the patient was treated by surgical excision of the lesion.DISCUSSIONThe intermittent symptomatology presentation on this case suggest a mechanical compression etiology, allied to classical pain and paresthesia often exhibited by this kind of the tumor. An intracompartimental pressure elevation could explain why the symptoms disclosed an episodic pattern, due to a constricted, inclosed nerve.CONCLUSIONWe describe a rare case of a patient with an unusual superficial peroneal nerve Schwannoma clinical presentation. Literature on this topic is scarce and, therefore, this case report intends to add further data about this kind of lesion.

show abstract

“…They have the potential for malignant transformation, but the occurrence is exceedingly rare. 4 As described in this case report, our patient had undergone excision of the lesion 2 years prior to her operation. During the procedure, we were unable to find evidence of recurrence and the procedure was completed without difficulty.…”

mentioning

confidence: 86%

“…They are characterized by interstitial hyalinization, degenerative atypia, and large hyperchromatic nuclei within cells. 4 The treatment approach toward ancient schwannomas is similar to that of typical schwannomas. They have the potential for malignant transformation, but the occurrence is exceedingly rare.…”

mentioning

confidence: 99%

Laparoscopic Paraesophageal Hernia Repair With Nissen Fundoplication in a Patient With Ancient Schwannoma of the Gastroesophageal Junction

Enciso

Stadsvold

Bolduc

et al. 2023

The American Surgeon™

View full text Add to dashboard Cite

Schwannomas are mostly benign tumors that originate from Schwann cells and are rarely seen in the gastrointestinal tract. Our patient is a 65-year-old female who was found to have a 1.5 cm lesion at the gastroesophageal junction, which was clipped and excised on endoscopy. Histologic examination demonstrated an ancient schwannoma. Two years afterward, she presented to our clinic for a large type III paraesophageal hernia. We took her to the operating room for a laparoscopic paraesophageal hernia repair and Nissen fundoplication. We performed an upper endoscopy during the case and found no recurrence of the ancient schwannoma. The case progressed well without complications. She was discharged on postoperative day 1 after tolerating a pureed diet and reported no issues in follow-up. In summary, we demonstrate a successful surgical outcome in a patient who had undergone resection of this rare tumor 2 years prior to her surgery.

show abstract

Ancient Schwannoma

Cited by 5 publications

References 3 publications

Degenerated (Ancient) Schwannomas: Unraveling Unusual Locations and Treatment Management

Degenerated (Ancient) Schwannomas: Unraveling Unusual Locations and Treatment Management

Ancient Schwannoma of superficial peroneal nerve presenting as intermittent leg pain: A case report

Laparoscopic Paraesophageal Hernia Repair With Nissen Fundoplication in a Patient With Ancient Schwannoma of the Gastroesophageal Junction

Contact Info

Product

Resources

About