2015
DOI: 10.1016/j.ijscr.2014.11.051
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Ancient Schwannoma of superficial peroneal nerve presenting as intermittent leg pain: A case report

Abstract: INTRODUCTIONSchwannomas are benign, encapsulated, slow-growing and usually solitary tumors originating from Schwann cells of the peripheral nerve sheath. Schwannomas of the superficial peroneal nerves are very rare, and therefore scarcely documented in the literature. The authors report a case of a diagnosed superficial fibular nerve sheath tumor with an unreported clinical presentation.PRESENTATION OF CASEA 52-year-old Caucasian female arrived to our Orthopedics Department complaining of pain and numbness of … Show more

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Cited by 19 publications
(16 citation statements)
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“…The term ancient schwannoma, which is not an indicator of malignancy, is used to describe an old schwannoma that has undergone degenerative changes over time (this variant of schwannoma is also rare). Degenerative changes that characterize an ancient schwannoma include interstitial hyalinization, cyst formation, calcification and haemorrhage, along with degenerative nuclear atypia, but without any mitotic activity [4,6,7] . MPNST are soft tissue neoplasms that have different types of differentiation towards one particular cellular structure of the nerve sheath.…”
Section: Case Presentationmentioning
confidence: 99%
“…The term ancient schwannoma, which is not an indicator of malignancy, is used to describe an old schwannoma that has undergone degenerative changes over time (this variant of schwannoma is also rare). Degenerative changes that characterize an ancient schwannoma include interstitial hyalinization, cyst formation, calcification and haemorrhage, along with degenerative nuclear atypia, but without any mitotic activity [4,6,7] . MPNST are soft tissue neoplasms that have different types of differentiation towards one particular cellular structure of the nerve sheath.…”
Section: Case Presentationmentioning
confidence: 99%
“…3 In our case, we performed complete surgical resection of the tumor. Six months later, the patient was able to walk without assistance and without pain.…”
mentioning
confidence: 91%
“…CS most often occurs in the 4 th and 5 th decades of life, without significant evidence of sex predilection. 3 Histopathologically, CSs are typically encapsulated by perineurium and are characterized by two types of histological patterns: Antoni type A and Antoni type B. Antoni A is a highly ordered cellular pattern in which spindle cells are arranged in compact fascicles and their nuclei are arranged in palisades. Verocay bodies are a characteristic feature in Antoni type A pattern, with collagen matrix arranged into palisading.. Antoni type B tissue exhibits a looser structure of mucinous matrix and it's less cellular.…”
mentioning
confidence: 99%
“…Los schwannomas de miembros inferiores son generalmente raros. En India han reportado una prevalencia de entre el 13,5 % y el 17,5 % de todos los casos de este tipo neoplasia [3], que contrasta con las cifras reportadas por otros investigadores europeos y americanos, que indican que la presencia en miembros inferiores es de aproximadamente el 1 % [7]. Clínicamente su crecimiento es asintomático, hasta que es detectado de forma incidental o presenta sintomatología por compresión mecánica que genera dolor, inflamación o palpación de masa [8].…”
Section: Introductionunclassified