Anchors and Sutures

Haslam, Sean; Barber, F. Alan

doi:10.1007/978-1-4471-5427-3_12

Cited by 2 publications

(2 citation statements)

References 34 publications

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“…In regard to nonabsorbable sutures, polyblend (Fiberwire, Herculine, Orthocord, and Ultrabraid) and conventional polyester (Ethibond) suture materials are used in rotator cuff surgery (8). In the last decade, polyblend sutures comprising Ultra-High-Molecular-Weight Polyethylene (UHMWPE) have become preferred because of their enhanced biomechanical properties (9). Polyblend sutures' biomechanical superiority to polyester suture materials has been previously demonstrated (10).…”

Section: Introductionmentioning

confidence: 99%

Rotator Cuff Repair with Different Suture Materials Results in Different Protein Expressions with Similar Histological Findings. An Experimental Study in Rabbits

Okay

Bezer

2020

Muscle Ligaments and Tendons J

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Background. Previous studies have evaluated the biomechanical, histological, and clinical effects of rotator cuff repair with different suture materials. However, a histological and western blot analysis after repair comparing nonabsorbable polyester and polyethylene suture materials in a chronic rotator cuff tear model has not been conducted in any previous studies. The aim of this study is to evaluate the effect the two different suture materials, specifically Ethibond and Ultrabraid, have on repair based on a histological evaluation and protein expression by means of a western blot analysis. Methods. Twenty-six rabbits were included in the study. Two rabbits served as normal controls (control group). A bilateral tenotomy of the subscapularis tendon was performed in the remaining 24 rabbits. Six weeks after the tenotomy, the animals were randomly divided into four repair groups (five rabbits in each group) according to the suture material used and the sacrifice time (Ultrabraid two weeks after repair, Ethibond two weeks after repair, Ultrabraid six weeks after repair, and Ethibond six weeks after repair). Two sham-operated groups with two rabbits each were sacrificed at eight and 12 weeks after the tenotomy without repair. Both shoulders of all the animals were used for a western blot (collagen type 1-3, MMP-2, TGF-beta-1, IGF-1, COX-2) analysis and a histological evaluation (fibrocartilage formation, inflammation, vascularisation, collagen density). Results. All groups showed minimal-to-mild histological changes irrespective of the type of suture material used. There was no statistically significant difference in histological scores (p > 0.05). Fibrocartilage formation was greater at six weeks in the polyester suture repair groups without statistical significance (p > 0.05). Collagen type 1-3, MMP-2, TGF-beta-1, IGF-1, and COX-2 were significantly upregulated at two weeks compared to six weeks after repair (p < 0.05). Protein expression levels were statistically significantly higher in the Ultrabraid groups compared to the Ethibond groups (p < 0.05). Conclusions. Changes in the expression of the markers related to rotator cuff healing were demonstrated when repairing with different suture materials, with these being in favour of polyester sutures; however, the histological findings are similar. This finding could influence the design of new suture materials.

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Section: Introductionmentioning

confidence: 99%

Rotator Cuff Repair with Different Suture Materials Results in Different Protein Expressions with Similar Histological Findings. An Experimental Study in Rabbits

Okay

Bezer

2020

Muscle Ligaments and Tendons J

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“…2,3 Absorbable sutures show good biological performances, 4 but their application in tendon/ligament repair is limited due to the degradation in vivo, which results in inferior mechanical support during the tendon/ ligament healing period. 2,5 Therefore, non-absorbable sutures continue to be the most widely used for tendon/ligament repair. 6 Nevertheless, it is reported that non-absorbable sutures with excessive strength are not ideal for tendon/ligament repair because of the resultant stress shielding, which hinders tissue remodeling and regeneration.…”

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confidence: 99%

Polycaprolactone/ultra-high molecular weight polyethylene partially absorbable suture with improved mechanical performances for tendon and ligament repair

Zhang

Luan

et al. 2020

Textile Research Journal

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Orthopedic suture, as an implantable surgical device for skeletal and soft tissue connection, is vital in tendon or ligament injury repair. Resorbable therapy approaches exhibit excellent biocompatibility in the field of suture materials but lack a long-term fixation effect in orthopedic treatment. Herein, this study focused on a series of partially absorbable orthopedic sutures, which were composed of absorbable polycaprolactone (PCL) multifilament and non-absorbable ultra-high molecular weight polyethylene (UHMWPE) multifilament. Comprehensive in vitro mechanical evaluations were conducted to probe the relationship between material composition and mechanical properties of the sutures. The results showed that the partially absorbable sutures, especially P/U = 50/50 and P/U = 25/75, exhibited significant improvements in mechanical properties compared to single-material sutures. The tensile strength of P/U = 50/50 and P/U = 25/75 was 180.99 and 210.91 N, respectively, which was about two times higher than that of absorbable PCL suture P/U = 100/0 (62.42 N). Furthermore, their suture-to-suture friction force was 1.89 times and 2.51 times that of non-absorbable UHMWPE suture P/U = 0/100, respectively, which guaranteed good knot security. Compared with the clinically used orthopedic suture Ethibond (110 N), P/U = 50/50 and P/U = 25/75 also presented superior tensile properties. Notably, P/U = 50/50 and P/U = 25/75 had similar tensile curves to that of the native tendon/ligament, which might be beneficial to tissue healing. Moreover, the R2 of Eyring's model to simulate the creep curves of each suture was higher than 0.99, which indicated that Eyring's model could be used in predicting the long-term creep behavior of the sutures.

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Anchors and Sutures

Cited by 2 publications

References 34 publications

Rotator Cuff Repair with Different Suture Materials Results in Different Protein Expressions with Similar Histological Findings. An Experimental Study in Rabbits

Rotator Cuff Repair with Different Suture Materials Results in Different Protein Expressions with Similar Histological Findings. An Experimental Study in Rabbits

Polycaprolactone/ultra-high molecular weight polyethylene partially absorbable suture with improved mechanical performances for tendon and ligament repair

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