2013
DOI: 10.1016/j.jdent.2013.08.012
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Anatomy of sodium hypochlorite accidents involving facial ecchymosis—A review

Abstract: Objectives Root canal treatment forms an essential part of general dental practice. Sodium hypochlorite (NaOCl) is the most commonly used irrigant in endodontics due to its ability to dissolve organic soft tissues in the root canal system and its action as a potent antimicrobial agent. Although NaOCl accidents created by extrusion of the irrigant through root apices are relatively rare and are seldom life-threatening, they do create substantial morbidity when they occur. Methods To date, NaOCl accidents have… Show more

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Cited by 109 publications
(93 citation statements)
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“…This irrigant solution may cause damage in contact with vital tissues (75,(80)(81)(82)(83). The accidents involving sodium hypochlorite may have some complications: severe pain; ballooning or immediate edema in soft tissue; extension of edema to a large area of the face, like the cheeks; periorbital ecchymosis on skin or mucosa as a result of profuse interstitial bleeding; profuse intraoral bleeding directly from root canal; palate mucosa necrosis; tissue necrosis; neurological complications; paresthesia; allergy; dermatological problems and life-threatening airway obstruction (80)(81)(82)(83).…”
Section: Isolation Of Tooth With Rubber Dammentioning
confidence: 99%
“…This irrigant solution may cause damage in contact with vital tissues (75,(80)(81)(82)(83). The accidents involving sodium hypochlorite may have some complications: severe pain; ballooning or immediate edema in soft tissue; extension of edema to a large area of the face, like the cheeks; periorbital ecchymosis on skin or mucosa as a result of profuse interstitial bleeding; profuse intraoral bleeding directly from root canal; palate mucosa necrosis; tissue necrosis; neurological complications; paresthesia; allergy; dermatological problems and life-threatening airway obstruction (80)(81)(82)(83).…”
Section: Isolation Of Tooth With Rubber Dammentioning
confidence: 99%
“…The mechanism of action includes biosynthetic changes; destruction of phospholipids; chloramines formation which interfere in cell metabolism; oxidative action with enzymatic inactivation in bacteria and degradation of fatty acids and lipids 9 . However, extrusion of this irrigating solution can cause intense reactions in the periapical tissues [10].…”
Section: Introductionmentioning
confidence: 99%
“…Prolonged inadvertent contact with host cells can lead to damage of the host cells resulting in pain and a chemically induced inflammatory reaction (Zhu et al 2013). Therefore, obtaining a balance between safety and effectiveness is important.…”
Section: Introductionmentioning
confidence: 99%