Anatomy and Morphological Study of Mentigi Gunung (Vaccinium varingiaefolium (Blume) Miq.) in Area of Mount Batok-Indonesia

Sholikhah, Annisa; Dian, Farida Aryani; Listyorini, Dwi

doi:10.18502/kls.v3i4.685

Cited by 6 publications

(4 citation statements)

References 2 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…is one of the plants. It belongs to Ericaceae family (Sholikhah et al, 2017). Cantigi grows well in the area close to sulphur vents or volcano region, such as Mount Tangkuban Parahu (MTP) having a peak at 2,081 meters above sea level (masl).…”

Section: Introductionmentioning

confidence: 99%

EFFECTS OF GELATIN AND GLUTARALDEHYDE CONCENTRATIONS ON CHARACTERISTICS OF CANTIGI (Vaccinium Varingiaefolium Miq.) EXTRACT LOADED GELATIN NANOPARTICLES AS ANTIOXIDANT

et al. 2021

View full text Add to dashboard Cite

Cantigi is an endemic plant of sub-alpine area of Mount Tangkuban Parahu in Bandung, Indonesia. Previous study showed ethanol extract of young red leaves had antioxidant activity, however no information on this activity if changed into nanoparticles. The purpose of this study was to determine the effects of gelatin and glutaraldehyde concentrations on the characteristics of Cantigi extract loaded gelatin nanoparticles and to evaluate the antioxidant activity of nanoparticles. Cantigi leaves were extracted by maceration using n-hexane, ethyl acetate, and ethanol 96%. The ethanol extract was dried, made into nanoparticles by varying gelatin (0.1; 0.2; and 0.3 g) and glutaraldehyde (0.1; 0.2; and 0.3 mL) amounts, and conducted at 500 rpm and 40 °C for 3 hours. Nanoparticles were evaluated for particle size, zeta potential, morphology, and antioxidant activity. Nanoparticles with glutaraldehyde amount variation had particle sizes (PS) of 105.9±26.2; 37.1±8.7; and 32.5±7.4 nm; polydispersity indeces (PI) of 0.508; 0.717; and 0.563; zeta potential values (ZPV) of 0.55; 0.89; and 0.78 mV; and antioxidant activities (IC50) of 56.15±0.16; 53.67±0.10; and 51.57±0.39 ppm, respectively. Then, nanoparticles with gelatin amounts variation had PS of 22.5±5.1; 37.1±8.7; and 83.3±21 nm; PI of 0.604; 0.717; 0.326; ZPV of 1.27; 0.89; 0.18 mV; and antioxidant activities of 51.58±0.19; 53.67±0.12; and 55.46±0.04 ppm, respectively. Nanoparticle morphology was spherical. Cantigi leaf extract can be made into gelatin nanoparticles; the smaller the concentration of the polymer used and higher the concentration of the glutaraldehyde, the smaller the resulted particle size and increased antioxidant activity. Antioxidant activities of nanoparticles was lower than those of the extract (IC50 16.84±0.30 ppm).

show abstract

Section: Introductionmentioning

confidence: 99%

EFFECTS OF GELATIN AND GLUTARALDEHYDE CONCENTRATIONS ON CHARACTERISTICS OF CANTIGI (Vaccinium Varingiaefolium Miq.) EXTRACT LOADED GELATIN NANOPARTICLES AS ANTIOXIDANT

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The internal secretory structures present a large distribution in four leaves, and the external secretory structures only present in D. kaki and C. cainito leaves. In V. varingiaefolium, the trichomes decrease and do not remain in some old stems, ripe fruit, and old leaves (Sholikhah et al 2015).…”

Section: Resultsmentioning

confidence: 96%

Histochemical Analysis of the Leaves of Four Ericales Medicinal Plants

Sabila¹,

Kusmardiyani²,

Insanu³

2022

Acta Pharm. Ind.

View full text Add to dashboard Cite

Active chemical compounds from medicinal plants are mostly secondary metabolites that can be histochemically tested. It enables the identification and localization of diverse secondary metabolites within the tissue, which is not possible with screening phytochemicals. In this study, the histochemistry of the leaf blades of Ericales plants i.e., cantigi (Vaccinium varingiaefolium (Blume) Miq.), persimmon (Diospyros kaki Thunb.), sapodilla (Manilkara zapota (L.) van Royen), and star apple (Chrysophyllum cainito L.) were evaluated. These species have been reported as folk medicines that have secondary metabolites. Each leaf tissue was observed under a microscope, and phytochemical compounds presence and location were detected by using specific reagents. The results showed that those four leaves contained phenols, flavonoids, and terpenes, while quinones were only found in cantigi leaves. The secondary metabolites were present in the idioblast of parenchymal and epidermal tissues. The persimmon and star apple leaves had secretory cavities in trichomes with terpenes and phenolic compounds.

show abstract

“…and S. myrtifolium Walp. were evaluated because they contain anthocyanin, a flavonoid chemical compound thought to effectively inhibit the activity of ACE [14], [15], [16], [27], [28]. In this research, Captopril is used as a positive control that has ACE inhibitory activity.…”

Section: Ace Inhibitory Activitymentioning

confidence: 99%

“…and S. myrtifolium Walp. contain anthocyanin flavonoids which are effective in inhibiting ACE activity [14], [15], [16]. Besides P. scutellarioides (L).…”

Section: Introductionmentioning

confidence: 99%

Potential Use of Some Indonesian Plants to Inhibits Angiotensin-converting Enzyme In Vitro

Sandhiutami

Dewi

Rahma

et al. 2022

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND: Some Indonesian plants, such as Vaccinium varingiaefolium Miq., Plectranthus scutellarioides (L.) R.Br., Syzygium myrtifolium Walp., and Eclipta prostrata (L.) L., are rich of flavonoid and anthocyanin. Flavonoid, flavan-3-ol, quercetin, anthocyanin, and tannin compounds can reduce systemic vascular resistance because they cause vasodilation and are thought to be able to influence the function of angiotensin-converting enzyme (ACE) and inhibit ACE activity, which plays an important role in the process of hypertension. AIM: This study aims to determine the potential of some Indonesian plants to inhibit ACE activity. METHODS: Testing of ACE inhibitory activity is carried out by the hippuric acid compounds formed as a result of the reaction between the substrate and the enzyme, then measured spectrophotometrically. The inhibitory and IC50 values of each test sample were compared with the positive control of Captopril. RESULTS: The four plant extracts contained secondary metabolites, such as flavonoids, tannins, saponins, quinones, steroids, triterpenoids, and essential oils. Ethanol extract of V. varingiaefolium Miq., P. scutellarioides (L.) R.Br., S. myrtifolium Walp., and E. prostrata (L.) L. each had an IC50 value of ACE inhibition activity of 131.4 ppm, 206. 7 ppm, 151.2 ppm, and 196.0 ppm. The IC50 value of the Captopril with inhibition of ACE activity is 11.1 ppm. CONCLUSION: This study shows that some Indonesian plants have the activity to inhibit the ACE and potential antihypertensive drug candidates with ACE inhibitory activity.

show abstract

Anatomy and Morphological Study of Mentigi Gunung (Vaccinium varingiaefolium (Blume) Miq.) in Area of Mount Batok-Indonesia

Cited by 6 publications

References 2 publications

EFFECTS OF GELATIN AND GLUTARALDEHYDE CONCENTRATIONS ON CHARACTERISTICS OF CANTIGI (Vaccinium Varingiaefolium Miq.) EXTRACT LOADED GELATIN NANOPARTICLES AS ANTIOXIDANT

EFFECTS OF GELATIN AND GLUTARALDEHYDE CONCENTRATIONS ON CHARACTERISTICS OF CANTIGI (Vaccinium Varingiaefolium Miq.) EXTRACT LOADED GELATIN NANOPARTICLES AS ANTIOXIDANT

Histochemical Analysis of the Leaves of Four Ericales Medicinal Plants

Potential Use of Some Indonesian Plants to Inhibits Angiotensin-converting Enzyme In Vitro

Contact Info

Product

Resources

About