Anatomy and functions of brain neurosecretory cells in diptera

Siga, Sakiko

doi:10.1002/jemt.10366

Cited by 47 publications

(33 citation statements)

References 132 publications

(172 reference statements)

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“…One continues medially and then projects ventrally to the subesophageal ganglia (SOG) via the median bundle, and to anterior subesophageal areas including the esophagus foramen and the ventral end of the anterior brain. The other runs ventrally to the esophagus foramen; this process is most likely the posterior lateral tract (PLT), as described for other cyclorrhaphous fly species (Shiga, 2003). Since the larval DL neurons terminate at the CC, we assume that adult DLP neurons also send projections to the CC in adult.…”

Section: Crz Expression Patterns In Adult Cnsmentioning

confidence: 96%

Comparative analysis ofCorazonin‐encoding genes (Crz's) inDrosophilaspecies and functional insights intoCrz‐expressing neurons

Choi

Lee

Hall

et al. 2005

J of Comparative Neurology

108

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To gain insight into regulatory mechanisms of tissue-specific Corazonin (Crz) gene expression and its functions in Drosophila, we cloned the Crz genes from four Drosophila species (D. melanogaster, D. simulans, D. erecta, and D. virilis) and performed comparative analyses of Crz gene sequences and expression patterns using in situ hybridization and immunohistochemistry. Although Crz gene sequences showed a great deal of diversity, its expression patterns in the CNS were highly conserved in the Drosophila species examined here. In D. melanogaster larva, Crz expression was found in four pairs of neurons per cerebral lobe and in eight pairs of bilateral neurons in the ventral nerve cord; in adult, the number of Crz-producing neurons increased to 6-8 in the pars lateralis of each brain lobe, whereas neurons in the ventral nerve cord were no longer detectable. Crz transcripts were also found in the optic lobes; however, these mRNAs do not seem to be translated. Such adult-like Crz expression patterns were established within 48 hours after pupation. Somata of Crz-neurons in the pars lateralis are located in the vicinity of terminals emanating from PDF-containing pacemaking neurons, indicating a functional connection between the two peptidergic nervous systems. A subset of Crz neurons coexpressed the period clock gene; however, normal Crz transcription was unaffected by central clockworks. Two pairs of ectopic Crz cells were detected in the adult brains of behaviorally arrhythmic Clock(Jrk) or cycle(02) mutants, suggesting that CLOCK and CYCLE proteins negatively regulate Crz transcription in a cell-specific manner.

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Section: Crz Expression Patterns In Adult Cnsmentioning

confidence: 96%

Comparative analysis ofCorazonin‐encoding genes (Crz's) inDrosophilaspecies and functional insights intoCrz‐expressing neurons

Choi

Lee

Hall

et al. 2005

J of Comparative Neurology

108

View full text Add to dashboard Cite

show abstract

“…The pars lateralis in the brain via its projections to the CA is the source of positive and negative control over JH production (Stay et al 1996, Stay 2000, Siga 2003. One of the neuropeptides reaching the CA was identified as allatostatin, which inhibits JH release.…”

Section: Neuroendocrine System Of Arthropodsmentioning

confidence: 99%

The neuroendocrine system of invertebrates: a developmental and evolutionary perspective

Hartenstein¹

2006

Journal of Endocrinology

247

216

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Neuroendocrine control mechanisms are observed in all animals that possess a nervous system. Recent analyses of neuroendocrine functions in invertebrate model systems reveal a great degree of similarity between phyla as far apart as nematodes, arthropods, and chordates. Developmental studies that emphasize the comparison between different animal groups will help to shed light on questions regarding the evolutionary origin and possible homologies between neuroendocrine systems. This review intends to provide a brief overview of invertebrate neuroendocrine systems and to discuss aspects of their development that appear to be conserved between insects and vertebrates.

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“…The clock neurons have two main projection targets: the accessory medulla that appears to be the principal pacemaker center of insects and the dorsal brain that houses the hormonal center (pars intercerebralis and lateralis) of insects and also has connections to most brain areas (Homberg et al 2003;Shiga 2003;for discussion, see Jaramillo et al 2004;Lear et al 2005a). The clock neurons form a well-defined fiber network in these brain areas, putatively allowing considerable cross-talk between them (Fig.…”

Section: Clock Neurons Of Drosophila Melanogastermentioning

confidence: 99%

The Lateral and Dorsal Neurons ofDrosophila melanogaster:New Insights about Their Morphology and Function

Helfrich‐Förster

Yoshii

Wülbeck

et al. 2007

Cold Spring Harbor Symposia on Quantitative Biology

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This chapter summarizes our present knowledge about the master clock of the fruit fly at the neuronal level. The clock is organized in distinct groups of interconnected pacemaker neurons with different functions. All of these neurons appear to communicate with one another in order to produce the species-specific activity rhythm, which is organized in morning (M) and evening (E) activity bouts. These two activity components are differentially influenced by distinct groups of pacemaker neurons reminiscent of the Pittendrigh-Daan dual oscillator model. In the original work (Grima et al. 2004;Stoleru et al. 2004), the ventrolateral (LN v ) and dorsolateral (LN d ) plus some dorsal groups (DN) of clock neurons have been defined as M and E cells, respectively. We further specify that the clock neurons belong to the M and E oscillators and define a more complex picture of the Drosophila brain clock.

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Anatomy and functions of brain neurosecretory cells in diptera

Cited by 47 publications

References 132 publications

Comparative analysis ofCorazonin‐encoding genes (Crz's) inDrosophilaspecies and functional insights intoCrz‐expressing neurons

Comparative analysis ofCorazonin‐encoding genes (Crz's) inDrosophilaspecies and functional insights intoCrz‐expressing neurons

The neuroendocrine system of invertebrates: a developmental and evolutionary perspective

The Lateral and Dorsal Neurons ofDrosophila melanogaster:New Insights about Their Morphology and Function

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