Anatomical Position of Hyaluronic Acid Gel Following Injection to the Eyebrow

Griepentrog, Gregory J.; Lucarelli, Mark J.

doi:10.1097/iop.0b013e31829a72bd

Cited by 13 publications

(16 citation statements)

References 11 publications

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“…4 Injection of HA gel into cadaveric infraorbital hollows resulted in a significant portion of the material outside the intended injection plane, while injections into the eyebrow region showed a consistent preperiosteal location. 5,6 In this study, dehydration of fresh frozen cadaver skin and subcutaneous tissues could have challenged accurate injection. In live injections, the practitioner would redirect the needle more superficially when the skin does not elevate during injection.…”

Section: Discussionmentioning

confidence: 97%

“…5,6 The specimens were then embedded in paraffin and a single 4 µm section was utilized. The section was stained with hematoxylin and eosin and examined with a light microscope to determine the histoanatomical location of HA.…”

Section: Methodsmentioning

confidence: 99%

“…[1][2][3] The microanatomical location of HA fillers has been described after in-vivo nasolabial fold injections, 4 and after infraorbital hollow and eyebrow injection in cadavers. 5,6 To the best of the authors' knowledge, there have been no histoanatomical studies directly evaluating HA gel position after injection within the temporal hollow. The authors sought to evaluate the position of HA gel using tissue histology after subcutaneous injection to the temporal hollows.…”

mentioning

confidence: 98%

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Microanatomical Location of Hyaluronic Acid Gel Following Injection of the Temporal Hollows

Chundury

Weber

McBride

et al. 2015

Ophthalmic Plastic &Amp; Reconstructive Surgery

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This study elucidates the location of hyaluronic acid gel after subcutaneous injection within the temporal hollow. Histology confirmed consistent placement of the gel within the subcutaneous tissues, but it also showed that injection in this region may produce unintended deeper location of filler, and a significant perivascular collection of the material. The proximity of dense temporal fascial and muscle arterial networks in this region may pose risk for perivascular injection and associated complications.

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Section: Discussionmentioning

confidence: 97%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 98%

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Microanatomical Location of Hyaluronic Acid Gel Following Injection of the Temporal Hollows

Chundury

Weber

McBride

et al. 2015

Ophthalmic Plastic &Amp; Reconstructive Surgery

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show abstract

“…8 Injection techniques commonly used are delivery of HA to the lateral one third of the eyebrow along the superior orbital rim to the preperiosteal plane or Retro Orbicularis Oculi Fat (ROOF) pad while using a retrograde linear threading technique. 3,6 The ROOF extends from the eyebrow to the upper lid giving shape to the eyebrow and may contribute to eyebrow ptosis, but treatment provides a smooth appropriate contour over the superior orbital rim. 6 However, the complex anatomy of the surrounding areas may pose the risk of long-term effects, especially if improper injection techniques are used.…”

Section: Discussionmentioning

confidence: 99%

Chronic eyelid edema and xerophthalmia secondary to periorbital hyaluronic acid filler injection

Khalil

Arnold

Seiger³

2019

J of Cosmetic Dermatology

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Background Hyaluronic acid (HA) is a popular, nonsurgical, temporary technique that is commonly used in the periocular region to restore volume in areas that have undergone volume loss, as well as adjusting the height and contour of the eyebrow. Aims Due to the location of glands, nerves, and vasculature, the facial anatomy should be well understood to avoid injections into areas that may result in complications. Patient/Methods A 54‐year‐old woman presented for a cosmetic consultation to address "puffy eyelids". She states she had HA filler injected along the orbital ridge inferior to the eyebrow and medially at the glabellar crease two years prior. Two months after her injection, she began to notice upper eyelid edema, xerophthalmia, and dryness of her nasal mucous membranes. Extensive evaluation and imaging were done by physicians of different specialties with a negative workup. Results A total of 60 units of hyaluronidase were injected into the areas of previous filler placement over a three‐week period. This resulted in complete resolution of the patient's presenting symptoms. Conclusion Familiarity with potential adverse events is arguably the most important aspect of treating patients with HA filler. The anatomy of the orbit and lacrimal system are important to keep in mind when evaluating symptoms related to possible long‐term complications of retained filler injections. Reporting this case should raise awareness about this potential adverse event and further explain the delicate anatomy of the periorbital area.

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“…Medical management with topical ointments with vitamin A derivate or chemical peels are recommended to take care of dyschromia and elastosis [3]. Aesthetic medicine corrections such as botulinum toxin injections and dermal fillers have been traditionally used for eyebrow lifting or skin dehydration [4][5][6][7].…”

Section: Discussionmentioning

confidence: 99%

Volumetric Eyebrow Lifting with the Aid of a New Hyaluronic Acid Dermal Filler (Intraline) and Upper Surgical Blepharoplasty; Enhancing Outcomes

Torres¹

2015

Clin Exp Dermatol Res

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Periocular aging is characterized for a volumetric skeletonization of the orbit, eyebrow ptosis and dystrophic changes in the eyelids skin, such as blepharochalasis, dyschromia and elastosis. Frequently only part of this elements are addressed, with incomplete resolution of the inestetisms, unnatural results and unsatisfied patients. Private setting patients with wishes of periocular rejuvenation were given combined approach of volumetric eyebrow lifting with the aid of a new hyaluronic acid dermal filler (Intraline Canada Inc, Kelowna BC, Canada) and upper surgical blepharoplasty. Through this combined method both volumetric changes, ptosis and blepharochalasis were corrected, and results in the short and medium term were satisfactory for both patients and surgeon. No complications were observed and the lengthening of the primary surgery was minimal in experienced hands.

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Anatomical Position of Hyaluronic Acid Gel Following Injection to the Eyebrow

Cited by 13 publications

References 11 publications

Microanatomical Location of Hyaluronic Acid Gel Following Injection of the Temporal Hollows

Microanatomical Location of Hyaluronic Acid Gel Following Injection of the Temporal Hollows

Chronic eyelid edema and xerophthalmia secondary to periorbital hyaluronic acid filler injection

Volumetric Eyebrow Lifting with the Aid of a New Hyaluronic Acid Dermal Filler (Intraline) and Upper Surgical Blepharoplasty; Enhancing Outcomes

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