“…In a rat endometriosis model, bevacizumab, VEGF-neutralizing monoclonal antibody, was shown to increase apoptosis [275]. Other drugs with anti-angiogenic effects confirmed in experimental endometriosis are celecoxib, a COX-2 inhibitor [276], and non-toxic fumagillin analogs, semisynthetic derivatives of a natural antibiotic, Aspergillus fumigatus [274]. The results of these Tumor suppressor ARID1A ± BAF250a mutation [94,95,96,105,209,[230][231][232][233] expressed [105,233] expressed [94,95,96,105,209,[230][231][232] PTEN somatic mutations [87-89, 93, 227, 228, 234] expressed [88,89,93,227,228] expressed [87,88,227,228,234] PIK3CA mutations [96,104,207] early event in endometriosis transformation [104] expressed [96,104,207] TP53 [90-92, 107, 213, 228, 229] expressed (late stages) [91,92,107,…”