Anaplastic KI-1 (CD30) Positive Large Cell Lymphoma of the Stomach Mimicking Hodgkin's Disease: A Case Report and Review of the Literature

Satti, Mohamed B.; Al‐Idrissi, Hassan Y.; Ismail, Mona H; Gindan, Yusuf M.; Al-Quorain, Abdulaziz

doi:10.5144/0256-4947.1999.352

Cited by 5 publications

(3 citation statements)

References 30 publications

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“…In the case of our patient the specimens initially immunologically stained were positive for CD30 and hence a misdiagnosis of CD30 positive large cell lymphoma was made. Apart from large cell lymphomas the CD30 antigen is expressed in various cell lineages such as malignant histiocytosis, plasmacytoma, some non-Hodgkin lymphomas other than large cell lymphoma, lymphomatoid papulosis and certainly Hodgkin's disease [ 3 , 13 ]. A full panel of immunohistochemical markers is hence essential to make an accurate diagnosis of gastric Hodgkin's disease.…”

Section: Discussionmentioning

confidence: 99%

Primary gastric Hodgkin's lymphoma

2007

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Section: Discussionmentioning

confidence: 99%

Primary gastric Hodgkin's lymphoma

2007

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“…There may be also some uncertainty in IHC investigation. CD30 antigen is expressed in Hodgkin disease and also in large cell lymphoma, in some non-Hodgkin lymphoma other than large cell lymphoma, in malignant histiocytosis, in plasmacytoma, in lymphomatoid papulosis [6,7]. Therefore, a full panel of IHC marker is essential to make accurate diagnosis of gastric Hodgkin lymphoma.…”

Section: Discussionmentioning

confidence: 99%

“…The diagnosis of Hodgkin's disease depends primarily on the detection of Reed-Steinberg cells on light microscopy and IHC staining. Exclusion of undifferentiated carcinomas, epitheloid sarcomas, diffuse large B cell lymphomas, natural killer/T cell lymphomas, anaplastic large cell lymphomas and malignant histiocytosis is required [3][4][5][6][7]. We report a case of primary gastric Hodgkin lymphoma and metachronous early gastric carcinoma.…”

Section: Introductionmentioning

confidence: 97%

Primary gastric Hodgkin lymphoma and metachronous early gastric carcinoma: a case report

Durnalı¹,

Tokluoğlu²,

Alkış³

et al. 2010

Med Oncol

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Primary Gastric Hodgkin lymphoma is seen very rarely. Primary gastric Hodgkin lymphoma and gastric carcinoma in same patient is very very rare entity. Almost all of the primary gastric lymphoma cases are non-Hodgkin lymphoma type. We report the case of 45-year-old man with 3-month history of abdominal pain and weight loss. Upper gastrointestinal endoscopic examination revealed an ulcerated polypoid mass on greater curve of stomach and histopathological examination of biopsy showed adenocarcinoma. After near total gastrectomy, gastric Hodgkin lymphoma diagnosis was made, and postoperative 4 courses of doxorubicin, bleomycin, vinblastine, dacarbazine (ABVD) regimen were administered, and then total 3,600 cGy radiotherapy was delivered. After 7 years, during control examination, early gastric carcinoma was diagnosed. Our case is very rare entity of gastric Hodgkin lymphoma and metachronous gastric carcinoma. This case also shows the importance of follow-up of patients not only for the relapse of primary disease but also for the development of secondary malignancy which can be diagnosed at early curable stage.

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