In recent years, several large earthquakes have struck Japan and brought severe destruction and human loss. As a lesson for the future, large amounts of data obtained from the earthquake aftermath reports were studied in order to attenuate the effect of future catastrophes. In this regard, the current study attempted to develop a risk assessment criteria through existing seismic data and mathematical models for machine tools at the time of seismic activity. Particularly, data from the 1995 Great Hanshin earthquake, the 2004 Chūetsu earthquake and the 2011 Tōhoku earthquake was considered for this research. Moreover, the risk managements regrading crashing or falling down of several machine tools in the machine shop at the large earthquake model were considered and evaluated by using the three calculation models for the parallel displacement, the rotational movement and the overturn. It was concluded that; (1) the risk managements regrading crashing or falling down of several machine tools in the machine shop at the large earthquake model were cleared; (2) The use of anchor bolts to fully secure the machine tool to the machine shop floor was very effective in preventing the machine tool from crashing and falling down.