Analytical methods for detection of Zika virus

Yang, Kai‐Hung; Narayan, Roger J.

doi:10.1557/mrc.2017.20

Cited by 8 publications

(7 citation statements)

References 57 publications

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“…Compared with eggs and animals, such cell cultures are cheap and convenient to examine through a microscope for the evidence of viral proliferation. Thus, cell cultures have been recognized as a desirable environment for viral isolation 226,310 . In brief, the samples are added into cell cultures and incubated at a controlled temperature for a specific period.…”

Section: Viral Isolationmentioning

confidence: 99%

“…With technological advances, the development of monoclonal antibodies and introduction of molecular diagnostics have offered powerful strategies for the detection of viral infections. Currently, viral isolation in cell culture serves as an unpractical tool for most clinical situations, and as such is primarily used for research purposes 226,312 …”

Section: Viral Isolationmentioning

confidence: 99%

“…Primary fibroblasts infected with ZIKV (MOI = 1) and mock‐infected cells were analyzed at various times postinfection for the presence of the viral envelope protein by immunofluorescence with 4G2 MAb and FITC‐conjugated anti‐mouse IgG. Reprinted with permission from Ref 226 . IgM, immunoglobulin M; MAC‐ELISA, IgM antibody capture enzyme‐linked immunosorbent assay; PRNT, plaque reduction neutralization test; ZIKV, Zika virus [Color figure can be viewed at wileyonlinelibrary.com]…”

Section: Serological Assaysmentioning

confidence: 99%

“…The discovery of ZIKV can be performed by detecting the viral components of ZIKV (e.g., viral proteins, RNA, or virus isolation), or measuring the antibody concentration against viral proteins of ZIKV (host immune response) through serological assays 96 . In recent years, there have been many strategies (Table 1) developed for the detection of ZIKV, including viral isolation, serological assays, molecular assays, and sensing methods 224‐232 . Recently, there have been some novel detection strategies developed for the detection of ZIKV, such as reverse transcription loop mediated isothermal amplification (RT‐LAMP), transcription‐mediated amplification (TMA) technology, reverse transcription strand invasion based amplification (RT‐SIBA), bioplasmonic paper‐based device (BPD), reverse transcription isothermal recombinase polymerase amplification, near‐infrared spectroscopy (NIRS), nanoparticle (NP)‐enhanced viral lysate electrical sensing assay, and smartphone‐based fluorescent lateral flow immunoassay.…”

Section: Introductionmentioning

confidence: 99%

“…The ZIKV diagnostic kits currently authorized by Emergency Use Authorization and commercially available kits for ZIKV detection have recently been evaluated 233,234 . While may reviews summarize the methods for the detection of ZIKV, they are not comprehensive, and just cover viral isolation, serological assays, and molecular assays 19,225,226,234,235 . Herein, we comprehensively summarize the strategies for detecting ZIKV (i.e., the viral isolation, serological assays, molecular assays, advanced sensing strategies, and other current state of the art methods).…”

Section: Introductionmentioning

confidence: 99%

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Recent progresses and remaining challenges for the detection of Zika virus

Zhang

Chen

et al. 2021

Medicinal Research Reviews

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Zika virus (ZIKV) has emerged as a particularly notorious mosquito‐borne flavivirus, which can lead to a devastating congenital syndrome in the fetuses of pregnant mothers (e.g., microcephaly, spasticity, craniofacial disproportion, miscarriage, and ocular abnormalities) and cause the autoimmune disorder Guillain‐Barre' syndrome of adults. Due to its severity and rapid dispersal over several continents, ZIKV has been acknowledged to be a global health concern by the World Health Organization. Unfortunately, the ZIKV has recently resurged in India with the potential for devastating effects. Researchers from all around the world have worked tirelessly to develop effective detection strategies and vaccines for the prevention and control of ZIKV infection. In this review, we comprehensively summarize the most recent research into ZIKV, including the structural biology and evolution, historical overview, pathogenesis, symptoms, and transmission. We then focus on the detection strategies for ZIKV, including viral isolation, serological assays, molecular assays, sensing methods, reverse transcription loop mediated isothermal amplification, transcription‐mediated amplification technology, reverse transcription strand invasion based amplification, bioplasmonic paper‐based device, and reverse transcription isothermal recombinase polymerase amplification. To conclude, we examine the limitations of currently available strategies for the detection of ZIKV, and outline future opportunities and research challenges.

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Section: Viral Isolationmentioning

confidence: 99%

Section: Viral Isolationmentioning

confidence: 99%

Section: Serological Assaysmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Recent progresses and remaining challenges for the detection of Zika virus

Zhang

Chen

et al. 2021

Medicinal Research Reviews

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Zika virus: epidemiology, clinical aspects, diagnosis, and control of infection

Karkhah

Nouri

Javanian

et al. 2018

Eur J Clin Microbiol Infect Dis

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Zika virus (ZIKV) is an emerging pathogen of huge public health significance to human beings. Although majority of infections are benign with self-limiting symptoms, the recent outbreak has established an association with the increased incidence of some congenital anomalies such as microcephaly. In other words, due to the large extent of the virus and mosquito vectors, the infection has become a thoughtful health problem for human societies, though now, there are no antiviral therapies or vaccines against this virus. In spite of extensive research carried out by scientists, not so much information has been gathered about this viral infection. In the current review, we prepared an overview of the remarkable progress made in understanding about the epidemiology, immunology, clinical presentation, and diagnosis methods of ZIKV infection.

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