Analytical Evaluation of Herbal Drugs

Kamboj, Anjoo

doi:10.5772/26109

Cited by 42 publications

(36 citation statements)

References 70 publications

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“…Traditional knowledge on herbal medicine has remained a mainstream source of maintaining wellbeing for generations in many communities (Kamboj, 2000). However, while many communities in Africa are custodian of sophisticated plant knowledge (Barrow, 1996), adoption of western culture has caused rapid erosion of indigenous knowledge (Fratkin, 1996).…”

Section: Introductionmentioning

confidence: 99%

Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

Kamau¹,

Mbaabu²,

Mbaria³

et al. 2016

TANG [HUMANITAS MEDICINE]

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In Kenya, traditional knowledge on herbal medicine has remained a mainstream source of maintaining wellbeing for generations in many communities. However, the knowledge has been eroded in the course of time due to sociocultural dynamics virtually advanced by Christianity and formal education especially in the Kikuyu community. The study documented current ethnobotanical knowledge and threat to the traditional knowledge on medicinal plants among the Kikuyu community. A survey was carried out in Mathira, Tetu, Kieni, Othaya, Mukurweini, and Nyeri Town constituencies. Thirty practicing herbalists were purposively sampled; 5 per constituency. Data was obtained through semi -structured questionnaires and analyzed both qualitatively and quantitatively. A total of 80 ailments treated using 111 medicinal plant species distributed within 98 genera and 56 families were documented. Prevalent communicable diseases treated using herbal medicine included; gonorrhea (17.5%), malaria (15%), respiratory infections (12%), colds (10%) and amoebiasis (10%). Non-communicable diseases were; joint pains (11.1%), ulcers/hyperacidity (8.7%), high blood pressure (8.7%), intestinal worms (11.1%) and arthritis/gout (10%). Frequently harvested plant materials were; roots, barks and leaves. The study concluded that, traditional medicine practitioners in Nyeri County possessed wide knowledge of herbal medicine but this knowledge was on the verge of disappearing as it was largely a preserve of the aged generation. The study recommended massive campaign about the benefits of using herbal medicine in the study area. Further pharmacological studies are recommended on the mentioned plant species aimed at establishing their efficacy and safety as well as standardization as potential drugs.

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Section: Introductionmentioning

confidence: 99%

Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

Kamau¹,

Mbaabu²,

Mbaria³

et al. 2016

TANG [HUMANITAS MEDICINE]

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“…Screening approach in research and development of phytopharmaceuticals Research and development of a herbal drug is usually different from those of a synthetic medicine whose active ingredient is known (Bandaranayake, 2006; Kamboj 2012). Recent approach to herbal medicine development follows random selection and screening of medicinal plant which has been selected from knowledge of traditional use or related literature information, and taken through conventional methods that combines biology and chemistry to determine active extract, fractions and isolated compounds, which are structurally elucidated and characterized (Table 1).Hence development is usually bioassay guided.…”

Section: Imentioning

confidence: 99%

“…These chemical screening approaches combine spectroscopic and chromatographic principles in analytical instruments which couple chromatographic equipment which help in the separation of chemical constituents based on chromatographic principles to spectroscopic equipment for the spectroscopic or spectrometric elucidation. For proteins and other charged groups, electrophoretic methods are deployed (Bandaranayake, 2006; Kamboj 2012).…”

Section: Imentioning

confidence: 99%

“…However, research and development approaches into traditional medicines in these countries, especially in Africa,is highly fragmented and suffers from poor coordination and strategic investment. Growing scientific evidence in recent times suggest significant contribution of traditional herbal preparations to ameliorating adverse health conditions leading to reduction of excessive mortality, morbidity and disability due to diseases such as malaria, chikungunya and dengue, African sleeping sickness, leishmaniasis, Chagas disease, tuberculosis, sicklecell anaemia, hypertension, diabetes, HIV/AIDS, and neurobehavioral and mental disorders ( 43 (1989) and several others recommended the inclusion of herbal medicine in the health care delivery system, and develop technical guidelines and standard methodologies for research as well as frameworks for their selection and inclusion in healthcare systems (Zhang, 1998;Bandaranayake, 2006;Kamboj, 2012).…”

Section: Introductionmentioning

confidence: 99%

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Chemical and Biological Screening Approaches to Phytopharmaceuticals

Ibrahim¹,

Egharevba²,

Gamaniel³

2017

ijSciences

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Abstract:The global demand for phytopharmaceutical products is on the upward trend and will probably continue to rise in the next few decades. This demand is fuelled by the growing acceptability, availability and affordability and the growing scientific evidence of efficacy. However, while great progress is being made in research and development of these products in the developed world, very little progress has been made in research, development and documentation of possible leads/products in developing countries of Africa. The challenges range from dearth of capacity to develop implement appropriate research protocols and tools. This article is an attempt toward providing a guide to the chemical and biologiocal screening approaches in the research and development of phytopharmaceuticals. Approaches towards achieving quality products that meets basic regulatory requirements are discussed.

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“…According to the estimate given by World Health Organization (WHO), 80% of the world population is dependent on alternate system of medicin e and natural health products. 5 Beetroot (Beta vulgaris L.) is a vegetable plant, belonging to the family Amaranthaceae. Beets are high in vitamin C, fiber and also contain some essential minerals like manganese and potassium.…”

mentioning

confidence: 99%

Evaluation of anti-inflammatory effect of beetroot extract in animal models

Adhikari

Saha²,

Indu

et al. 2017

Int J Basic Clin Pharmacol

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Background: Inflammation is complex biological response of body tissues to foreign particles or pathogens. However, adverse effects of anti-inflammatory drugs, necessitate the search for a novel compound from herbal origin. Beta vulgaris rubra or red beetroot, a vegetable plant, is known to possess various beneficial effects. Present study aimed to evaluate the anti inflammatory effect of beet roots in animal models.Methods: Carrageenan-induced and Complete Freund’s adjuvant-induced rat paw edema model were used to assess the acute and chronic anti- inflammatory potential of the Beetroot as compared to standard drug, Diclofenac Sodium.Results: Oral administration of Beetroot extract showed carrageenan-induced rat paw edema inhibition by 26.9%, 34.6% and 50% for beetroot 100mg/Kg, 200mg/Kg and 400mg/Kg, respectively, at the end of four hours. In vivo results noted that percentage inhibition of paw volume and ankle diameter of the Complete Freund’s adjuvant-induced rats were significantly higher for the groups consuming 100 and 200mg/Kg Beetroot extracts. Paw volume of the rats in these two groups reduced by 35% and 30% respectively as compared to the control.Conclusions: Thus, beetroot was found to possess anti-inflammatory property in animals. Further investigations are essential to validate the bioactive components responsible for this property.

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Analytical Evaluation of Herbal Drugs

Cited by 42 publications

References 70 publications

Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

Ethnobotanical survey and threats to medicinal plants traditionally used for the management of human diseases in Nyeri County, Kenya

Chemical and Biological Screening Approaches to Phytopharmaceuticals

Evaluation of anti-inflammatory effect of beetroot extract in animal models

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