Abstract:Background: Giant cell tumor of bone (GCTB) is a relatively common benign bone tumor, accounting for 4–9.5 % of all primary bone neoplasms. Localization of GCTB is one of the most important differential diagnostic criteria, since the tumor affects certain parts of the skeleton. Until now, surgical treatment was considered the method of choice in the treatment of GCTB. However, in recent years, denosumab, a genetically engineered drug, has been widely used to treat this tumor. Denosumab treatment of GCTB preven… Show more
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