“…High performance liquid chromatography mass spectrometry has been shown as a valuable alternative for detection of PPCPs and EDCs to overcome the drawbacks of GC-MS (Gardinali and Zhao, 2002;Gentili et al, 2002;Ingrand et al, 2003;Cahill et al, 2004;Castiglioni et al, 2005;Schlüsener and Bester, 2005;Martnez Bueno et al, 2007;Gros et al, 2009;Laven et al, 2009;Huerta-Fontela et al, 2010;Jian-lin et al, 2010). Electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) and atmospheric pressure photoionization (APPI) are the three most common ionization techniques coupled with liquid chromatography (Marchi et al, 2009).…”