Analysis of Risk Factors for Organic Erectile Dysfunction in Egyptian Patients Under the Age of 40 Years

Elbendary, Mohamed; El‐Gamal, Osama M.; Salem, Khaled

doi:10.2164/jandrol.108.007195

Cited by 32 publications

(33 citation statements)

References 23 publications

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“…The prevalence of ED among men under the age of 40 years was estimated to be about 1–9% [15]. Use of recreational drugs (OR: 3.18, 95% CI: 1.15–8.82) and smoking (OR: 1.78, 95% CI: 1.16–2.72) are the most significant risk factors for organic ED in patients under 40 years [16]. In our study, the drug users had onefold increase for the risk of ED than the controls after adjustment of other confounders.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Illicit Use of Amphetamine on Male Sexual Functions

Chou

Huang

Jiann

2015

The Journal of Sexual Medicine

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Introduction Data concerning the impact of amphetamine on male sexual functions are limited, although amphetamine has been used as an aphrodisiac. Aims This cross-sectional study was to assess the impact of illicit use of amphetamine on male sexual functions. Methods Male illicit drug users in a Drug Abstention and Treatment Center were recruited to complete a self-administered questionnaire, and data were compared with age-matched controls. Main Outcome Measures The International Index of Erectile Function (IIEF) and global assessment questions were used to assess sexual functions. Results Of 1,159 amphetamine mono-illicit drug users, the mean age was 31.9 ± 7.5 (18–57) years, and mean duration of drug use was 30.7 ± 52.2 (median 9, range 0.1–252) months. Half of them reported that drug use had no impact on their sexual functions. The other half reported drug impacts as reduced erectile rigidity and sexual life satisfaction, enhanced orgasmic intensity, and prolonged ejaculation latency time more often than the opposite effects, while they reported enhanced or reduced effect equally on sexual desire. Dosing frequency of amphetamine was associated with its impact on sexual functions, but duration of its use had little association with that. Compared with 211 age-matched controls, the amphetamine mono-illicit drug users had lower IIEF scores in the domains of erectile function, orgasmic function, and overall satisfaction, but there are no significant differences in intercourse satisfaction and sexual desire scores. The prevalence of erectile dysfunction (ED) was significantly higher in the drug users than in the controls (29.3% vs. 11.9%). The odds ratio of ED for amphetamine use was 2.1 (95% confidence interval 1.2–3.6) after adjustment for other risk factors. Conclusions The impact of illicit use of amphetamine on male sexual functions varied among users, and their ED prevalence was higher than the controls.

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Section: Discussionmentioning

confidence: 99%

The Impact of Illicit Use of Amphetamine on Male Sexual Functions

Chou

Huang

Jiann

2015

The Journal of Sexual Medicine

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“…In a specific cohort of young men <40 years of age, smoking was a significant risk factor for ED. In these men, the multivariate analysis did not show significance in other vascular risk factors strongly indicating a role for smoking in the pathogenesis of ED in younger men (Elbendary et al ., ). While the majority of these studies accounted for other vascular risk factors (i.e.…”

Section: Epidemiological Associations Between Ed and Smokingmentioning

confidence: 97%

Effects of cigarette smoking on erectile dysfunction

et al. 2014

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Summary Cigarette smoking is a leading cause of preventable morbidity and mortality in the United States. Although public policies have resulted in a decreased number of new smokers, smoking rates remain stubbornly high in certain demographics with 20% of all American middle aged men smoking. In addition to the well-established harmful effects of smoking (i.e coronary artery disease and lung cancer), the past three decades have led to a compendium of evidence being compiled into the development of a relationship between cigarette smoking and erectile dysfunction. The main physiological mechanism that appears to be affected includes the nitric oxide signal transduction pathway. This review details the recent literature linking cigarette smoking to erectile dysfunction, epidemiological associations, dose-dependency and the effects of smoking cessation on improving erectile quality.

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“…Smoking was presented as a significant risk factor for ED by Elbendary et al (2009) in their comparison of 434 patients with ED and 272 patients as controls under 40 years old, and a negative correlation between smoking index and IIEF-5 scores of patients with ED was detected. Smoking was presented as a significant risk factor for ED by Elbendary et al (2009) in their comparison of 434 patients with ED and 272 patients as controls under 40 years old, and a negative correlation between smoking index and IIEF-5 scores of patients with ED was detected.…”

Section: Discussionmentioning

confidence: 99%

“…Another risk factor for ED is smoking. Smoking was presented as a significant risk factor for ED by Elbendary et al (2009) in their comparison of 434 patients with ED and 272 patients as controls under 40 years old, and a negative correlation between smoking index and IIEF-5 scores of patients with ED was detected. These results were correlated with the results of Gades et al (2005) and Kupelian et al (2007).…”

Section: Discussionmentioning

confidence: 99%

Erectile dysfunction and depression in patients with chronic lead poisoning

et al. 2012

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In this retrospective study, we aimed to evaluate the relationship between erectile dysfunction (ED) and chronic lead intoxication (CLI) as well as the role of depression in this relationship. We compared the findings of 26 male patients with CLI and 24 male patients as the control group between November 2008 and January 2009. The blood lead levels and smoking index of patients were evaluated for both groups. The International Index of Erectile Dysfunction-erectile function domain (EFD) and Beck Depression Inventory (BDI) were obtained and reviewed in both groups. The mean blood lead levels of patients in the CLI and control groups were 42.1 and 3.2 μg dl(-1) respectively (P < 0.01). The mean interval of lead exposure of patients in CLI group was 71.5 (6-360) months. EFD scores of patients in CLI group were significantly lower, and number of patients with ED in CLI group was statistically higher (P < 0.05). BDI scores of patients in CLI group were significantly higher (P < 0.05). We detected a mildly negative and statistically significant relationship between the EFD scores and blood lead levels (r = -0.453 and P < 0.05). Our results showed that the increased frequency of ED is an independent factor in CLI group.

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Analysis of Risk Factors for Organic Erectile Dysfunction in Egyptian Patients Under the Age of 40 Years

Cited by 32 publications

References 23 publications

The Impact of Illicit Use of Amphetamine on Male Sexual Functions

The Impact of Illicit Use of Amphetamine on Male Sexual Functions

Effects of cigarette smoking on erectile dysfunction

Erectile dysfunction and depression in patients with chronic lead poisoning

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