Analysis of rhythm variation during spontaneous cardioinhibitory neurally-mediated syncope. Implications for RDR pacing optimization: an ISSUE 2 substudy

Brignole, Michele; Sutton, Richard; Wieling, Wouter; Lu, Shichao; Erickson, Mark; Markowitz, Toby; Grovale, Nicoletta; Ammirati, Fabrizio; Benditt, David G.

doi:10.1093/europace/eum017

Cited by 26 publications

(16 citation statements)

References 19 publications

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“…Some patients with neurocardiogenic syncope have underlying sinus bradycardia and associated high vagal tone. Furthermore, the premonitory rate drop prior to syncope can be rather prolonged, with a total duration of the cardioinhibitory reflex lasting 85 seconds (range 47-116 seconds) (116). An atrial (AAI) pacemaker should not be used in an individual who may have episodic transient AV block due to augmented parasympathetic activation.…”

Section: Neurocardiogenic Syncopementioning

confidence: 99%

HRS/ACCF Expert Consensus Statement on Pacemaker Device and Mode Selection

Gillis¹,

Russo²,

Ellenbogen³

et al. 2012

Journal of the American College of Cardiology

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Section: Neurocardiogenic Syncopementioning

confidence: 99%

HRS/ACCF Expert Consensus Statement on Pacemaker Device and Mode Selection

Gillis¹,

Russo²,

Ellenbogen³

et al. 2012

Journal of the American College of Cardiology

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“…AV block during neurocardiogenic reflex is rare, although it has been documented during vasovagal and situational syncope. 75,76 AV block provoked by tilt test represents the cardioinhibitory component of the neurocardiogenic reflex which is less frequent than sinus arrest, sinoatrial block, or sinus bradycardia (vagal stimulation on sinoatrial node usually predominates). Zysko et al reported an incidence of 5.2% of complete AV block in patients with positive tilt test, 77 similar to what had been previously found.…”

Section: Vagally Induced Atrioventricular Blockmentioning

confidence: 99%

Erratum

2012

Pacing Clinical Electrophis

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Complete atrioventricular block is a relatively uncommon arrhythmia that is nonetheless increasingly (PACE 2012; 35:1395-1405 complete atrioventricular block, atrioventricular block etiology, cardiac conduction IntroductionComplete heart block, also referred to as thirddegree heart block or third-degree atrioventricular (AV) block, is a disorder of the cardiac conduction system where there is complete dissociation of the atrial and ventricular activity due to the absence of conduction through the atrioventricular node (AVN) or His-Purkinje system. Although Mobitz I second-degree AV block is observed in 1-2% of healthy young people, especially during sleep, the prevalence of third-degree AV block is only 0.02% in the United States and 0.04% worldwide.1,2 Its incidence increases with advancing age (highest in people older than 70 years), despite an early peak in infancy and early childhood due to congenital

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“…The ILR is implanted subcutaneously in the left hemithorax with automatic and patient-activated ECGdocumentation modes available on most devices. Many studies have shown its value in detection of infrequent arrhythmias [39][40][41] . Current guidelines suggest ILR implantation for unexplained syncopes.…”

Section: The Implantable Loop Recordermentioning

confidence: 99%

Management and therapy of vasovagal syncope: A review

Aydın¹

2010

WJC

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Vasovagal syncope is a common cause of recurrent syncope. Clinically, these episodes may present as an isolated event with an identifiable trigger, or manifest as a cluster of recurrent episodes warranting intensive evaluation. The mechanism of vasovagal syncope is incompletely understood. Diagnostic tools such as implantable loop recorders may facilitate the identification of patients with arrhythmia mimicking benign vasovagal syncope. This review focuses on the management of vasovagal syncope and discusses the non-pharmacological and pharmacological treatment options, especially the use of midodrine and selective serotonin reuptake inhibitors. The role of cardiac pacing may be meaningful for a subgroup of patients who manifest severe bradycardia or asystole but this still remains controversial.

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Analysis of rhythm variation during spontaneous cardioinhibitory neurally-mediated syncope. Implications for RDR pacing optimization: an ISSUE 2 substudy

Cited by 26 publications

References 19 publications

HRS/ACCF Expert Consensus Statement on Pacemaker Device and Mode Selection

HRS/ACCF Expert Consensus Statement on Pacemaker Device and Mode Selection

Erratum

Management and therapy of vasovagal syncope: A review

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