Analysis of Retinal Microstructure in Eyes with Dissociated Optic Nerve Fiber Layer (DONFL) Appearance following Idiopathic Macular Hole Surgery: An Optical Coherence Tomography Study

He, Shucheng; Ye, Xin; Qiu, Wangli; Yang, Shangchao; Zhong, Xiaxing; Chen, Yiqi; He, Rui; Shen, Lijun

doi:10.3390/jpm13020255

Cited by 3 publications

(1 citation statement)

References 37 publications

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“…The study, however, did not specifically assess metamorphopsia symptoms or fully explore the potential impacts of displacement on visual function. Therefore, it is crucial to note that the traditional procedure of ILM peeling, involving the disruption of Müller cell peduncles, inevitably leads to some retinal damage in the peeled area 33 , 34 . The investigation of the mechanisms that cause damage will help us to understand the potential damage of ILM movement, to a certain extent, and assist surgeons in making more informed decisions regarding the surgical approach and its timing.…”

Section: Discussionmentioning

confidence: 99%

The impact of preoperative parameters on postoperative foveal displacement in idiopathic macular hole

Qin,

Zhao,

Jin

et al. 2024

Sci Rep

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This study examined the effect of vitrectomy combined with internal limiting membrane (ILM) peeling on foveal displacement in 42 eyes with idiopathic macular hole (IMH). A retrospective analysis was conducted to measure various macular hole parameters before surgery, including basal diameter, minimum diameter, hole height, and areas affected by traction such as macular hole area (MHA), macular hole cystoid space area (MHCSA), macular hole retinal area (MHRA), and total area (TA). The results showed a postoperative shift of the fovea towards the optic disc in all cases. Notably, the extent of foveal displacement was significantly linked to the preoperative basal diameter (rs = 0.405, P = 0.008) but not to other preoperative parameters or postoperative visual acuity. Furthermore, the study found that the temporal side of the macular hole was more affected by traction than the nasal side preoperatively, leading to greater postoperative displacement (All P < 0.05).

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Section: Discussionmentioning

confidence: 99%

The impact of preoperative parameters on postoperative foveal displacement in idiopathic macular hole

Qin,

Zhao,

Jin

et al. 2024

Sci Rep

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Three-Dimensional Quantitative Analysis of Internal Limiting Membrane Peeling Related Structural Changes in Retinal Detachment Repair

Hsieh,

Wang,

Chen

et al. 2024

American Journal of Ophthalmology

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Pros and cons of internal limiting membrane peeling during epiretinal membrane surgery: a randomised clinical trial with microperimetry (PEELING)

Ducloyer,

Eude,

Volteau

et al. 2024

Br J Ophthalmol

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BackgroundAfter idiopathic epiretinal membrane (iERM) removal, it is unclear whether the internal limiting membrane (ILM) should be removed. The objective was to assess if active ILM peeling after iERM removal could induce microscotomas.MethodsThe PEELING study is a national randomised clinical trial. When no spontaneous ILM peeling occurred, patients were randomised either to the ILM peeling or no ILM peeling group. Groups were compared at the month 1 (M1), M6 and M12 visits in terms of microperimetry, best-corrected visual acuity (BCVA) and optical coherence tomography findings. The primary outcome was the difference in microscotoma number between baseline and M6.Results213 patients were included, 101 experienced spontaneous ILM peeling and 100 were randomised to the ILM peeling (n=51) or no ILM peeling group (n=49). The difference in microscotoma number between both groups was significant at M1 (3.9 more microscotomas in ILM peeling group, (0.8;7.0) p=0.0155) but not at M6 (2.1 more microscotomas in ILM peeling group (−0.5;4.7) p=0.1155). Only in the no ILM peeling group, the number of microscotomas significantly decreased and the mean retinal sensitivity significantly improved. The ERM recurred in nine patients in the no ILM peeling group (19.6%) versus zero in the ILM peeling group (p=0.0008): two of them underwent revision surgery. There was no difference in mean BCVA and microperimetry between patients experiencing or not a recurrence at M12.ConclusionSpontaneous ILM peeling is very common. Active ILM peeling prevents anatomical ERM recurrence but may induce retinal impairments and delay visual recovery.Trial RegistrationNCT02146144.

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Analysis of Retinal Microstructure in Eyes with Dissociated Optic Nerve Fiber Layer (DONFL) Appearance following Idiopathic Macular Hole Surgery: An Optical Coherence Tomography Study

Cited by 3 publications

References 37 publications

The impact of preoperative parameters on postoperative foveal displacement in idiopathic macular hole

The impact of preoperative parameters on postoperative foveal displacement in idiopathic macular hole

Three-Dimensional Quantitative Analysis of Internal Limiting Membrane Peeling Related Structural Changes in Retinal Detachment Repair

Pros and cons of internal limiting membrane peeling during epiretinal membrane surgery: a randomised clinical trial with microperimetry (PEELING)

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