Analysis of Prognostic Factors Relating to Postoperative Survival in Spinal Metastases

Yang, Soon Bum; Cho, Won Ik; Chang, Ung-Kyu

doi:10.3340/jkns.2012.51.3.127

Cited by 59 publications

(39 citation statements)

References 35 publications

(79 reference statements)

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“…Yang et al (217 patients) analyzed the prognostic factors associated with survival time after a spinal metastasis operation and found that patients who underwent decompressive laminectomy without instrumentation had a median survival of 5.0 months, whereas those who underwent decompressive laminectomy with instrumentation had a median survival of 9.0 months, and the difference between the two was not significant. 36 These authors also analyzed anterior corpectomy and did not stratify survival, complications, functional status, or other factors by tumor type or operation.…”

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confidence: 99%

Posterior approaches for symptomatic metastatic spinal cord compression

Molina

Goodwin

Abu-Bonsrah

et al. 2016

FOC

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Surgical interventions for spinal metastasis are commonly performed for mechanical stabilization, pain relief, preservation of neurological function, and local tumor reduction. Although multiple surgical approaches can be used for the treatment of metastatic spinal lesions, posterior approaches are commonly performed. In this study, the role of posterior surgical procedures in the treatment of spinal metastases was reviewed, including posterior laminectomy with and without instrumentation for stabilization, transpedicular corpectomy, and costotransversectomy. A review of the literature from 1980 to 2015 was performed using Medline, as was a review of the bibliographies of articles meeting preset inclusion criteria, to identify studies on the role of these posterior approaches among adults with spinal metastasis. Thirty-four articles were ultimately analyzed, including 1 randomized controlled trial, 6 prospective cohort studies, and 27 retrospective case reports and/or series. Some of the reviewed articles had Level II evidence indicating that laminectomy with stabilization can be recommended for improvement in neurological outcome and reduction of pain in selected patients. However, the use of laminectomy alone should be carefully considered. Additionally, transpedicular corpectomy and costotransversectomy can be recommended with the expectation of improving neurological outcomes and reducing pain in properly selected patients with spinal metastases. With improvements in the treatment paradigms for patients with spinal metastasis, as well as survival, surgical therapy will continue to play an important role in the management of spinal metastasis. While this review presents a window into determining the utility of posterior approaches, future prospective studies will provide essential data to better define the roles of the various options now available to surgeons in treating spinal metastases.

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confidence: 99%

Posterior approaches for symptomatic metastatic spinal cord compression

Molina

Goodwin

Abu-Bonsrah

et al. 2016

FOC

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“…17 Patient-specific indications include life expectancy The stereotactic radiosurgery treatment plan. 17 Patient-specific indications include life expectancy The stereotactic radiosurgery treatment plan.…”

Section: Integration Of Radiosurgery With Spinal Surgerymentioning

confidence: 99%

“…17 There are typically three patient populations that would benefit from radiosurgery. This stands in contrast to conventional radiotherapy, in which typically 10 doses of 3 Gy each are given over the course of 2 weeks.…”

Section: Clinical Indications For Isolated Spinal Radiosurgerymentioning

confidence: 99%

The Integration of Radiosurgery for the Treatment of Patients With Metastatic Spine Diseases

Sharan¹,

Szulc

Krystal³

et al. 2014

Journal of the American Academy of Orthopaedic Surgeons

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Significant evidence emerging in the spinal oncology literature recommends radiosurgery as a primary modality of treatment of spinal metastasis. Improvements in the methods of delivering radiation have increased the ability to provide a higher and more exacting dose of radiation to a tumor bed than previously. Using treatment-planning software, radiation is contoured around a specific lesion with the intent of administering a tumoricidal dose. Combined with a minimally invasive, tumor-load reducing surgery, this advanced form of radiation therapy can provide better local control of the tumor compared with conventional external beam radiation.

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“…Approximately 20 % of spinal metastasis cases exhibit neurological deficit due to spinal cord compression [4]. Untreated spinal metastasis results in the deterioration of life quality due to severe neurological deficits and intractable pain, which can shorten life expectancy with complications [5].…”

Section: Introductionmentioning

confidence: 99%