Analysis of oncology research from 2001 to 2010: A scientometric perspective

Abstract

Over the past half-century, the incidence of tumours has increased, resulting in cancer becoming one of the most lethal diseases in humans. In the present study, we elucidated the status of oncology research from 2001 to 2010. Studies published in 30 representative oncology journals were retrieved from the Web of Science (2001-2010) to compose our dataset. Knowledge domain visualisation, co-citation analysis and social network analysis methods were used. By mapping the oncology research performed from 2001 to 2010, we identified the primary research centres, including the top 20 institutions and countries and the 4 major oncology research fronts: i) the mechanism of abnormal oncogene expression; ii) tumour metastasis and angiogenesis; iii) the relationship between cancer cells and apoptosis; and iv) tumour vaccines. We also identified the 36 most collaborative academic communities, and multiple myeloma, angiogenesis and acute lymphocytic leukaemia were found to be the focuses of collaborative research in oncology from 2001 to 2010. Over the past 10 years, America has led oncology research, while China is the sole developing country to be ranked in the top 10. Analyses of the main research centres and forefronts may assist researchers in addressing these forefronts and ascertaining the developing trends in oncology. Analysis of the academic communities performing oncology research may provide scientific evidence and suggestions for policymakers to select the most prolific academic groups and leaders and to effectively manage and finance future oncology research. These selected groups and individuals will carry out additional joint undertakings and solve complex problems encountered in oncology research.

Scientific impact of studies published in temporarily available radiation oncology journals: a citation analysis

“…Citation rate of published articles was chosen to define the most important contributions. Articles with high numbers of citations are likely those that impressed other clinicians/scientists and had impact on clinical practice or future developments in the field (Shao et al 2013). It should be noticed that searches in different databases will result in more or less variable citation counts and that the present results therefore provide only a snapshot.…”

Vaccination of multiple myeloma: Current strategies and future prospects

“…By mapping the oncology research performed from 2001 to 2010, Shao et al identified the four major oncology research fronts: the mechanism of abnormal oncogene expression, tumor metastasis and angiogenesis, the relationship between cancer cells and apoptosis, and finally, tumor vaccine [120].…”

Current and Evolving Methods to Visualize Biological Data in Cancer Research

“…In contrast to transit map diagrams, network diagrams are algorithmically generated via a variety of computational methods (eg, www.genemania.org). Network analysis is often used to illustrate multidimensional "-omics" datasets such as genomics, transcriptomics, and metabolomics ( Figure 7A) but can also be used to represent any group of interconnected variables such as academic authorship ( Figure 7B) (47,48).…”

“…Journals could play a key role here, standardizing features like colors used to describe stage, histology, or chromosomes, or the symbols used in plots like swim plots. Bringing consensus to data representation will speed the (48). One vertex represents one author.…”