Analysis of IL-10 in HIV-1 patients with chronic periodontitis in northern Brazil

Menezes, Sílvio Augusto Fernandes de; Menezes, Tatiany Oliveira de Alencar; Rodrigues, Tânia Maria de Souza; Nogueira, Brenna Magdalena Lima; Fonseca, Ricardo Roberto de Souza

doi:10.20396/bjos.v16i0.8651054

Cited by 4 publications

(13 citation statements)

References 16 publications

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“…The assessment was made using a Williams periodontal probe (Hu-Friedy, Chicago, IL, USA), a mouth mirror, and clinical tweezers, all of which were sterile, consisted of disposable materials, and were used under natural lighting. The following clinical parameters were assessed: CAL, bleeding on probing (BoP) and probing depth (PD) 12 .…”

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confidence: 99%

“…Patients with gingivitis should have inflamed and edematous gingiva with swelling of the interdental papilla, easily induced bleeding, and no CAL. Patients younger than 20 years, pregnant women, lactating women, diabetics, smokers, and patients on systemic or local antimicrobial therapy, on hormone replacement therapy, or on any analgesic and anti-inflammatory drugs less than 30 days prior to sample collection were excluded from the study 12 .…”

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confidence: 99%

“…To confirm that all individuals were HIV-1 positive, blood samples were collected and sent to the clinical laboratory for diagnostic purposes. ELISA type immunoenzyme assay was performed (DiaSorin, anti-HIV tetra Elisa, Biotest, Germany), which includes a recombinant antigen, one of the envelope and two antigens of the viral capsid 8,12 .…”

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confidence: 99%

“…One CR monitored the patients and collected the clinical reports. Data were collected and averaged between the sites collected divided by the number of teeth examined per patient 12,13 .…”

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confidence: 99%

“…Besides the collections from the pockets, saliva was also sampled by placing the Endo points in the sublingual region for 1 minute. Each tip was placed in a sterile polystyrene tube (Eppendorf, Sigma, CA, USA) which was sealed and identified with patient data and the site where the sample was collected and was immediately sent, under refrigeration in a cooler with ice packs, to the Laboratory of Virology of the Federal University of Pará and stored at -70ºC until analysis 8,12,13 .…”

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confidence: 99%

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Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil

Fonseca

Alves

Amanajás

et al. 2018

Rev. Soc. Bras. Med. Trop.

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Introduction: The influence of cytomegalovirus (CMV) on the progression of chronic periodontitis in HIV patients is poorly investigated. Methods: ELISA was used for anti-CMV antibody IgG titer measurements and real-time polymerase chain reaction for qualitative and quantitative CMV detection. Data on the CD 4 + T lymphocyte count and plasma HIV viral load were obtained from patient records. Results: CMV DNA was detected in samples of subgingival biofilm in only three individuals, two of them with chronic periodontitis (4%) and one with gingivitis (3.3%). Conclusions: The prevalence of CMV is very low both in HIV-1 patients with gingivitis and chronic periodontitis.

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confidence: 99%

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confidence: 99%

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confidence: 99%

“…One CR monitored the patients and collected the clinical reports. Data were collected and averaged between the sites collected divided by the number of teeth examined per patient 12,13 .…”

mentioning

confidence: 99%

mentioning

confidence: 99%

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Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil

Fonseca

Alves

Amanajás

et al. 2018

Rev. Soc. Bras. Med. Trop.

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Severe Necrotizing Periodontitis in an HIV‐Infected Patient: Case Report and Non‐Surgical Treatment

Fonseca

Carvalho

Rodrigues

et al. 2020

Clin Adv Periodontics

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Introduction Necrotizing periodontitis (NP) is an atypical and painful form of periodontal disease, it is described by a promptly progress of ulceration and destruction of periodontal tissues; the NP is commonly linked to HIV‐positive patients. The aim of this report is to present a rare case of severe necrotizing ulcerative periodontitis treated non‐surgically. Case Presentation A 28‐year‐old dark skin female patient was referred to a dentistry college with the main complaint of spontaneous gingival bleeding and enlargement, oral pain during deglutition and dental hypersensitivity. Clinical and radiographic examination revealed generalized severe periodontal destruction, extensive bleeding, increased biofilm presence and spontaneous suppuration. Medical exams were requested, red and white blood cells were evaluated and among those exams an enzyme‐linked immunosorbent assay for HIV‐1 antibodies, the result reveled reagent to HIV‐1. The diagnosis of NP was assigned based on periodontal parameters such as necrosis and ulceration of the coronal portion of interdental papillae and gingival margin. Treatment established was scaling and root planning plus antibiotics. At 3 months of treatment the clinical and periodontal condition were stable. Conclusion This case report highlights a severe and generalized form of NP, where periodontal non‐surgical associated with antimicrobials resulted in elimination of the gingival enlargement, necrosis and ulceration of the coronal portion of interdental papillae and significant improvement of periodontal parameters.

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Systemic management and periodontal treatment of HIV‐necrotizing periodontitis: A case report

Golob Deeb,

Elnakka,

Deeb

2023

Clin Adv Periodontics

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BackgroundNecrotizing periodontitis (NP) is a rare form of periodontal disease. It can manifest in immunocompromised patients and present as painful and rapidly progressing destruction with necrotic and ulcerated periodontal tissues. This case report describes a rare case of severe NP in human immunodeficiency virus (HIV)‐positive patient including medical management and periodontal treatment.MethodsA 28‐year‐old male presented to the periodontal clinic with chief complaint of severe oral pain leading to loss of chewing ability, spontaneous gingival bleeding, generalized gingival recession, tooth mobility, and dentinal hypersensitivity. Clinical and radiographic examination revealed generalized tissue necrosis with severe periodontal destruction, extensive bleeding, spontaneous suppuration, and heavy biofilm.ResultsMedical history was positive for perinatal HIV infection, which was treated and patient was asymptomatic until he discontinued antiviral medications nine years ago. Following initial examination, patient was referred to the Infectious disease clinic and multidisciplinary management was initiated with comprehensive management of primary disease including systemic antiviral, antibiotic, and antifungal therapy to establish immunocompetence compatible with providing mechanical nonsurgical periodontal treatment.ConclusionsThis case report highlights a severe and generalized form of NP in an HIV patient due to the cessation of antiviral therapy. Favorable course of interdisciplinary medical and periodontal therapy resulted in significant improvement in patient's systemic, oral, and periodontal health.

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Analysis of IL-10 in HIV-1 patients with chronic periodontitis in northern Brazil

Cited by 4 publications

References 16 publications

Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil

Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil

Severe Necrotizing Periodontitis in an HIV‐Infected Patient: Case Report and Non‐Surgical Treatment

Systemic management and periodontal treatment of HIV‐necrotizing periodontitis: A case report

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