“…[1][2][3]9,16 However, the ANS also can be evaluated via measures of autonomic reserves by assessing a patient's response to an autonomic challenge, such as the Valsalva maneuver, 17,18 a tilt table, 19 or a neuraxial block. 20, 21 In fact, clinicians could speculate that the ability to respond to an autonomic challenge may better reflect the capacity of patients to sustain anesthesia and surgery than baseline autonomic values. 22 Because of the frequent association between cardiovascular disease and autonomic dysfunction, most patients scheduled for cardiac surgery should have some degree of autonomic dysfunction.…”