Mining the hidden dysrhythmia ‐ can machines get smarter at defining the anaesthetised state?

Kurata, Jiro

doi:10.1111/anae.13314

Cited by 2 publications

(2 citation statements)

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“…As has been highlighted in a recent editorial , anaesthetic practitioners often estimate the effectiveness of anaesthesia without using objective methods, with experience and ‘a sixth sense’ playing a major role. A pioneering method of monitoring depth of anaesthesia, using, among other things, physiological parameters and heart rate variability, has recently been described .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the relationship between baseline autonomic tone and the vagotonic effect of a bolus dose of remifentanil

et al. 2016

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SummaryRemifentanil stimulates the parasympathetic nervous system, and patients with increased parasympathetic tone may be at greater risk of bradycardia after its administration. We aimed to establish if adult patients with increased baseline parasympathetic tone were at higher risk of bradycardia and hypotension when given a bolus dose of remifentanil. Seventy adults (age 20-60 years and ASA physical status 1 or 2) were given remifentanil 1 lg.kg À1. A Holter ECG monitor was used to assess heart rate changes. Heart rate variability in the frequency domain during the 5 min after remifentanil administration was analysed. Multivariate analysis demonstrated that baseline heart rate was the only independent predictor of remifentanil-induced bradycardia [odds ratio (95% CI) 0.877 (0.796-0.966)]. The vagotonic action of remifentanil does not appear to be related to baseline autonomic tone in adult patients.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the relationship between baseline autonomic tone and the vagotonic effect of a bolus dose of remifentanil

et al. 2016

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“…Such anaesthesia in the real world would highly complicate the coherent interactions among the different systems of the body. The state of general anaesthesia does not necessarily implicate the binary states of consciousness or a linear measure of anaesthetic depth, but rather encompasses biologically heterogeneous conditions where multiple agents act on various receptors in multiple organs and systems of the body to a variable extent [12].…”

Section: The Brain Is Not the Sole Target Of Anaesthesiamentioning

confidence: 99%

The World Health Organization safe surgery checklist as a catalyst for system improvement

Hannenberg

2015

Anaesthesia

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Mining the hidden dysrhythmia ‐ can machines get smarter at defining the anaesthetised state?

Cited by 2 publications

References 12 publications

Evaluation of the relationship between baseline autonomic tone and the vagotonic effect of a bolus dose of remifentanil

Evaluation of the relationship between baseline autonomic tone and the vagotonic effect of a bolus dose of remifentanil

The World Health Organization safe surgery checklist as a catalyst for system improvement

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