Analysis of Clinical Efficacy of Traditional Chinese Medicine in Recovery Stage of Stroke: A Systematic Review and Meta-Analysis

Abstract

Background. We provide an updated meta-analysis with detailed information on a combination of TCM and routine treatment. Methods. Retrieve appropriate articles with no language restrictions on keywords until 8 July 2019 in an electronic database. All trajectories are screened according to certain criteria. The quality of certified research was also evaluated. We made a detailed record of the results of the measurement. Meta-analysis was carried out by using the Revman 5.3 software. Results. Sixty-seven RCTs were included, and 6594 subjects were analyzed. Compared with routine treatment, the total effective rate (TER) of TCM combined with routine treatment was improved, and the recovery of stroke was also significantly accelerated. Regulation of blood lipids by notably shrinking the contents of TC, TG, and LDL and enhancing the levels of HDL. The levels of serum hs-CRP, WHV, and WLV decreased significantly, indicating that the expression of thrombomodulin was decreased after the comprehensive treatment of traditional Chinese medicines (TCMs). The combination of TCM treatment could enhance the protection of neural function by decreasing the NIHSS scoring while increasing the BI scoring. Paeoniae Radix Rubra, Angeticae Sinensis Radix, etc., can effectively improve the clinical symptoms of stroke convalescent patients and promote the recovery of neurological function. ACU of Baihui, Renzhong, etc., can improve the clinical rehabilitation effect of patients. However, our findings must be handled with care because of the small sample size and low quality of clinic trials cited. Other rigorous and large-scale RCTs are in need to confirm these results. Conclusion. A combination of TCM and routine treatment in the treatment of stroke could improve TER, and it is beneficial to the rehabilitation of patients in the recovery period of apoplexy. These effects can be mediated by a combination of several mechanisms. Nevertheless, due to the limitations of this study, these results should be handled with caution.

Effect of Grading Rehabilitation Nursing Mode on Limb Function, Speech Rehabilitation, and Quality of Life of Stroke Patients

“…Prevention of stroke requires timely control of the primary disease, improvement of unhealthy lifestyles and habits, followed by initiation of secondary prevention therapy, which mainly includes blood pressure control, antipolymerization and lipid regulation plus plaque stabilization; moreover, combination of the three methods can reduce the risk of stroke. 80% incidence [ 21 , 22 ]. Chinese medicine emphasizes on stroke care: maintain emotional well-being and reduce adverse stimulation; keep the room sunny and ventilated; eat more light, digestible, high-quality protein-rich foods; carry out traditional Chinese medicine special care, such as cupping, acupuncture and traditional Chinese medicine fumigation; often observe the vital signs and state of consciousness of the patients in the acute stage, and pay attention to the nursing of the second bowel movement [ 23 , 24 ].…”

Acupuncture and Traditional Chinese Herbal Medicine Integrated With Conventional Rehabilitation for Post-stroke Functional Recovery: A Retrospective Cohort Study

“…A recent meta-analysis study demonstrated that Paeoniae Rubra Radix (Chi Shao), Angelicae Sinensis Radix (Dang Gui), Astragali Radix (Huang Qi), Puerariae Lobatae Radix (Ge Gen), and Salviae Mihiorrhizae Radix et Rhizoma (Dan Shen) could relieve the symptoms of convalescent stroke patients, promote neurological function recovery, and improve the ADL effectively ( Zhang et al, 2020 ). Many Chinese herbs or herbal formulations (such as Salviae Mihiorrhizae Radix et Rhizoma (Dan Shen), Notoginseng Radix et Rhizoma (San Qi), Astragali Radix (Huang Qi), Bu Yang Huan Wu Tang, and Dang Gui Shao Yao San) have demonstrated significant pro-angiogenic and neuroprotective effects ( Seto et al, 2016 ).…”

Effectiveness of traditional Chinese medicine in treating gastrointestinal dysfunction in patients with acute stroke: a systematic review and meta-analysis of 16 randomized controlled trials

“…A study conducted by Zhang (26) concluded that TCMs combined with routine treatment affect the blood lipid by regulating the contents of TC, TG, LDL, and HDL, and are beneficial to the rehabilitation of patients in the recovery period of apoplexy.…”