Analysis of Antimicrobial Activity of <i>Woodfordia fruticosa, Adhatoda vasica</i> and <i>Ricinus communis</i> Against Multi-Drug Resistant Bacteria

Joshi, Mahavir; Kaur, Sukhminderjit; Verma, Monika; Mishra, Tulika

doi:10.5958/0974-360x.2019.00505.5

Cited by 4 publications

(3 citation statements)

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“…The TPC of the MPEs of the four plants was also estimated and demonstrated in Figure (1). It has been found that the extract of S. spinosum possess the highest amount of phenolic compounds (320mg GA/g dry extract), followed by I. viscosa and A. fragrantissima (258 and 112mg GA/g dry extract, respectively).…”

Section: Total Phenolic Content (Tpc)mentioning

confidence: 96%

“…The fresh samples of four medicinal plants were collected from their natural environment at Wadi Al-Karak region which is located in Al-Karak governorate/Jordan. The botanical data of those plants are demonstrated in Table (1). The plants were identified and classified by Prof. Saleh Al-Quran who is a plant taxonomist in the Department of Biology, Faculty of Sciences, Mu'tah University, Jordan.…”

Section: Plant Materialsmentioning

confidence: 99%

“…This was due to the increasing global interest in human health and the emergence of multi-drug resistant microbes. Infectious diseases caused by multi-drug resistant bacteria are a major problem to public health 1,2 . This problem is still developing and there are still some uncertainties regarding the future use of antimicrobial drugs 3 On the other hand, the natural antioxidants that are present in natural products can prevent the oxidative deterioration of foods especially those with high contents of lipids 4 .…”

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confidence: 99%

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Evaluation of the Antibacterial and Antioxidant properties of the Methanolic extracts of four Medicinal plants selected from Wadi Al-Karak, Jordan related to their Phenolic contents

Alfarrayeh

Tarawneh

Al-Majali

et al. 2022

RJPT

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In this study, the methanolic extracts from four medicinal plants (Sarcopoterium spinosum, Paronychia argentea, Inula viscosa, and Achillea fragrantissima) were tested in vitro for antibacterial and antioxidant properties. The antibacterial properties of these MPEs were assessed using disc diffusion and Serial dilution techniques. The antioxidant properties were evaluated by DPPH and FRAP methods. The total phenolic compounds were measured according to Folin-Ciocalteu method. Differences were found among the tested plants in their antibacterial and antioxidant properties as well as the phenolic content. Among the four plants, I. viscosa revealed the highest antibacterial effects against all bacterial species under examination followed by S. spinosum. Gram-positive bacteria showed higher susceptibility to the MPEs than Gram-negative bacteria. Antioxidant capacity and polyphenolic content investigations revealed that S. spinosum and I. viscosa have the highest antioxidant activities and the highest amount of phenolic compounds. Moreover, a strong positive linear correlation was found between antioxidant activity and total phenolic content. In conclusion, the MPEs of I. viscosa and S. spinosum have been proven to have good antibacterial and antioxidant activities which were highly related to their contents of phenolic compounds. These plant extracts could be interesting sources for natural antibacterial and antioxidant agents.

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Section: Total Phenolic Content (Tpc)mentioning

confidence: 96%

Section: Plant Materialsmentioning

confidence: 99%

mentioning

confidence: 99%

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Evaluation of the Antibacterial and Antioxidant properties of the Methanolic extracts of four Medicinal plants selected from Wadi Al-Karak, Jordan related to their Phenolic contents

Alfarrayeh

Tarawneh

Al-Majali

et al. 2022

RJPT

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Multifunctional analysis and antimicrobial activity of Adhatoda vasica: a traditional medicinal plant

Fatima,

Zafar,

Ain

et al. 2023

Drug Metabolism and Personalized Therapy

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Objectives Antibiotic resistance is rising, prompting innovative strategies for eradicating the epidemic. This study investigated the antibacterial properties of the leaves of a widely used medicinal plant, Adhatoda vasica. Methods The plant’s polar (water, methanol) and non-polar (hexane) extracts were tested against several different bacterial strains using the disc diffusion technique. Results In a study, it was found that the water extract had the greatest inhibitory effect on Staphylococcus simulans and Staphylococcus aureus, with minimum inhibitory concentrations of 16.444 and 19.315 g/mL, respectively. Gram-negative strains were more susceptible to plant extracts than Gram-positive strains. The phytochemical analysis indicated the presence of secondary metabolites such as alkaloids, saponins, flavonoids, tannins, and steroids, where absorbance was recorded at 415 nm. The water extract had the highest amount of phenolics, with a total phenolic content of 53.92 0.47 mg and a total flavonoid content of 7.25 0.08 mg. Results suggest that the extract may have potential therapeutic applications for antimicrobial properties. Conclusions The study concluded that the extract’s phenolic group of secondary metabolites were responsible for its antibacterial activity. The study highlights A. vasica as a promising source for discovering new and effective antibacterial compounds.

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Study of Toxin ‘Ricinine’ present in Ricinus communis by TLC and GC-MS A Forensic Perspective

Yadav

Singla

Gupta

et al. 2022

RJPT

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Ricinus communis popularly known as castor plant belongs to the family of Euphorbiaceae. The whole plant had a great potential of being used in bio terrorism all around the world. In the view of forensic investigations, the plant contains an active principle component ‘ricin’ which is highly toxic to people, animals and insects frequently encountered in cases such as suicidal, accidental and homicidal deaths. In the present study, fresh leaves extract of the plant was used for phytochemical screening of the alkaloids in both methanol and n-hexane solvents. The result showed the presence of alkaloids such as steroids, saponins, tannins, glycosides, and Flavonoids. Thin layer chromatography was performed for preliminary examination of the main toxins using the solvent system (petroleum ether, diethyl ether and acetic acid in 80:18:2 v/v/v ratio). The poly complex structured compounds of the leaf extract were analyzed by using GC-MS. The chromatogram obtained revealed the presence of ricinine, heptadecane, octadecane, Pentadecane, 2,6,10-trimethyl, sulfurous acid, pentyl tetradecyl ester, hexadecane, 3-pyridinecarbonitrile, 2,6,10,14-tetramethyl, octadecane, 2-methyl, nonadecane, 9-methyl, phthalic acid, di(6-methylhept-2-yl) ester, 1,2-Benzenedicarboxylic acid, mono(2-ethylhexyl) ester, 1,2-benzenedicarboxylic acid, bis-(3,5,5-trimethylhexyl) phthalate in the leaf extract of Ricinus communis.

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Analysis of Antimicrobial Activity of Woodfordia fruticosa, Adhatoda vasica and Ricinus communis Against Multi-Drug Resistant Bacteria

Cited by 4 publications

References 0 publications

Evaluation of the Antibacterial and Antioxidant properties of the Methanolic extracts of four Medicinal plants selected from Wadi Al-Karak, Jordan related to their Phenolic contents

Evaluation of the Antibacterial and Antioxidant properties of the Methanolic extracts of four Medicinal plants selected from Wadi Al-Karak, Jordan related to their Phenolic contents

Multifunctional analysis and antimicrobial activity of Adhatoda vasica: a traditional medicinal plant

Study of Toxin ‘Ricinine’ present in Ricinus communis by TLC and GC-MS A Forensic Perspective

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