Analysis of aluminum-26 labeled aluminum chlorohydrate

Flarend, Richard; Keim, Craig; Tao, Bo; Elmore, D.; Hem, Stanley L.; Ladisch, Michael R.

doi:10.1016/s0162-0134(99)00127-0

Cited by 6 publications

(4 citation statements)

References 10 publications

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“…Very limited analytical measurements were available for the ACH [10]. Atomic absorption based detection technique was often used for the Aluminum containing real sample analyses [11 -13].…”

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confidence: 99%

Detection of Aluminum Chlorohydrate Content in Antiperspirant Deodorants Using Screen‐Printed Silver Electrodes by One Drop Analysis

et al. 2009

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Aluminum chlorohydrate (Al(2)(OH)(5)Cl center dot 2H(2)O, ACH) is an active ingredient in many antiperspirants and deodorants formulation to reduce the body odors (mainly sweat) through interaction with apocrine sweat glands to produce insoluble aluminum hydroxide and free chloride, which then plugs the sweat gland that stops the flow of sweat to the skin's surface. We demonstrated here an one drop (50 mu L) electrochemical sensing of the ACH using an in-built three screen-printed electrodes assembly containing Ag as working and pseudo reference and carbon as counter electrode system (AgSPE). The free Cl(-) ion librated from ACH/H(2)O reaction was detected at AgSPE surface at 0.072 V vs. pseudo Ag reference electrode system in pH 2 phosphate Solution by Cyclic voltammetric Technique. Under optimal working condition the AgSPE shows a linear calibration plot in the window of 30-2000 ppm of ACH with sensitivity and regression values of 0.104 mu A/ppm and 0.998 respectively. Calculated detection limit is 3.03 ppm. RSD values of intra- and interassays were 0.19% and 2.79% respectively. Finally, real sample (antiperspirant deodorant lotions) assays were successfully demonstrated with results comparable to the predicted values

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“…Very limited analytical measurements were available for the ACH [10]. Atomic absorption based detection technique was often used for the Aluminum containing real sample analyses [11 -13].…”

mentioning

confidence: 99%

Detection of Aluminum Chlorohydrate Content in Antiperspirant Deodorants Using Screen‐Printed Silver Electrodes by One Drop Analysis

et al. 2009

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“…The most important representatives of this group of actives are aluminium and zirconium salts which reduce sweat by causing mechanical obstruction to the eccrine sweat duct at the acrosyringium level. These active ingredients are mainly complexes which differ only in the relative amounts of aluminium, chloride, and zirconium [159]. Aluminium-based compounds in antiperspirants are characterized by an acidic pH value, thus being responsible for the acidity of the entire formulation (pH ranging from 3.5 to 4.5) [160].…”

Section: Antiperspirantsmentioning

confidence: 99%

An Overview of Novel Surfactants for Formulation of Cosmetics with Certain Emphasis on Acidic Active Substances

Lukić¹,

Pantelić²,

Savić³

2016

Tenside Surfactants Detergents

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Novel surfactants which are nowadays available for incorporation into various formulations of personal care and cosmetic products are numerous, implying a permanent need for their classification. This overview provides essential information relating to synthesis, basic physicochemical characteristics, application and other relevant data on surfactants currently used in cosmetic products. In the second part of the paper an outline of acidic active substances with significant application in cosmetic products is given, as well as the problems that arise during preparation/manufacture of the containing formulations, accompanied with the review of scientific publications and other available reliable data dealing with the incorporation of these actives in the cosmetic formulations stabilized with novel (mainly natural) surfactants.

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“…The spectrometric determination of aluminum in antiperspirants has been described using several methods as UV‐Vis spectrophotometry, [7–9] molecular fluorescence spectrometry, [10–12] atomic absorption spectrometry, [13] inductively coupled plasma optical emission spectrometry, [14,15] and others. Most of them require complex chemical derivatization, time‐consuming sample preparation steps, or rely on expensive analytical instrumentation, which can be a limiting factor for some applications.…”

Section: Introductionmentioning

confidence: 99%

“…[6] In spite of the occurrence of high Al levels in breast tissues and human exposure to this metal on daily basis, several studies associating aluminum with health damage have been addressed over the last decades, but most findings were inconclusive or lacked evidence. [5] The spectrometric determination of aluminum in antiperspirants has been described using several methods as UV-Vis spectrophotometry, [7][8][9] molecular fluorescence spectrometry, [10][11][12] atomic absorption spectrometry, [13] inductively coupled plasma optical emission spectrometry, [14,15] and others. Most of them require complex chemical derivatization, time-consuming sample preparation steps, or rely on expensive analytical instrumentation, which can be a limiting factor for some applications.…”

Section: Introductionmentioning

confidence: 99%

Direct Determination of the Aluminum Content in Antiperspirants Using Digital Image Colorimetry

Teixeira,

Virgilio,

Santos

2023

ChemistrySelect

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In this work a dilute‐and‐shoot procedure using digital image colorimetry (DIC) was evaluated for the determination of aluminum in antiperspirants. Derivatization was performed by means of the reaction between Al(III) and Alizarin Red S (ARS) reagent. Digital images were acquired using a table scanner and the average values for red, green and blue channels (RGB) were obtained. Optimal conditions were set at pH=4.5, ARS concentrations 10‐fold higher than Al(III) and using the G channel. The method presented linearity in the 2.0–10.0 mg L−1 range, the limit of detection (LOD) was 1.1 mg L−1 and precision was better than 2.55 %. Accuracy was checked by the analysis of spiked samples at 2.0 and 4.0 mg L−1 Al(III), and good recoveries (82.6–117.5 %) were obtained. Eight samples of roll‐on antiperspirants were analyzed by the proposed colorimetric method and the well‐stablished flame atomic absorption spectrometry (FAAS) comparative method. The obtained results were not statistically different at 95 % confidence level. An analytical greenness assessment was performed for both methods and the procedure based on digital image colorimetry was proven to be a greener approach due to miniaturization, low sample consumption, least amount of waste and high sample throughput.

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Analysis of aluminum-26 labeled aluminum chlorohydrate

Cited by 6 publications

References 10 publications

Detection of Aluminum Chlorohydrate Content in Antiperspirant Deodorants Using Screen‐Printed Silver Electrodes by One Drop Analysis

Detection of Aluminum Chlorohydrate Content in Antiperspirant Deodorants Using Screen‐Printed Silver Electrodes by One Drop Analysis

An Overview of Novel Surfactants for Formulation of Cosmetics with Certain Emphasis on Acidic Active Substances

Direct Determination of the Aluminum Content in Antiperspirants Using Digital Image Colorimetry

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