This article offers new insight into a set of issues related to modern digital technologies in higher education. Also, there are analyzed their impact and some specific aspects of the dynamic interaction between them in today's context of higher education. The impact of the Fourth Industrial Revolution (4IR) on the mission of higher education from universities is also explored. Modern digital technologies in higher education are a necessity in the current student-centered education system, focusing on the level of development of its potential, to develop an efficient, sustainable learning style that correlates different operational concepts for maintaining high academic standards.