In the twenty-first century, neglected tropical diseases still remain a serious public health problem, especially in developing countries. Meeting several sustainable development objectives of the 2030 Agenda, by countries that are in this condition, will provide the population with another level of quality of life. In Brazil, this situation is far from being resolved, since its dimensions are continental, there is a lot of social inequity, lack of basic services, health, and education. In this context, the scenario of the last 10 years of six neglected tropical diseases that are classified as notifiable in Brazilian territory is presented. There are several public policies established by the Federal government containing actions, strategies, and programs to try to reduce the burden of these diseases, but there is a lack of political will for states and municipalities to comply with the established in order to achieve all objectives and goals. It is still necessary to have an active participation of the population so that the reduction process can be started for possible elimination.