Análise dos eventos adversos pós-vacinais ocorridos em Teresina

Abstract

This study focuses the profile of the adverse events after-vaccine occurrences in Teresina in 2006. The data had been collected by means of the form application with 73 participants in 18 Basic Units of Health. The results show that the vaccines that had more produced events adverse had been tetravalente, BCG and DPT The events most frequent had been: fever, hiporresponsivo hipotonic episode, moderate irritability and local manifestations. Amongst the behaviors adopted for the health professionals, 80% had been approximately adjusted. The year minors had been accomitted by the events. All the events had evolved for the cure. It was concluded that the action of vaccination still continues requiring constant qualification of the professionals of the area. It is suggested to deepen the knowledge with relation to the handling, diagnosis, inquiry and treatment.

Prevalência e fatores associados à ocorrência de eventos adversos pós-vacinação em crianças

“…(19) In this study, HHE were the most prevalent event, and other severe and unusual events associated with the tetravalent and pentavalent vaccines were registered. Studies conducted in Teresina and Campo Grande verified HHE as the second and fourth (8,15) most prevalent event, and fever > 39.5º, pain, flushing, and heat as the most prevalent events.…”

“…(1,14) The high frequency of AEFI in children under one year old found in this study was also evidenced in other studies. (7,8,15) This study points out that in this age group there is a higher concentration of vaccines applied and the immune system is still immature, increasing the probability of infectious processes, allergies, and clinical alterations that may be associated with immunization. (13,14,16,17) The present study evidenced the predominance of AEFI in children aged between 3 and 6 months.…”

“…Other studies associated AEFI with DTP (15) and BCG. (8) The tetravalent vaccine was implemented in the routine of immunization of the Unified Health System in 2002 and the pentavalent vaccine in 2012. The combination of vaccines enables a reduction of operational and logistic costs and provides a higher level of comfort to users (displacements to health units, number of injections applied, and reduction in the occurrence of local manifestations associated with less exposure).…”

“…Other authors also reported similar outcomes. (8,12,13) Information on vaccine safety, contraindications, and the possible occurrences of AEFI are necessary for the control of immunopreventable diseases. Ignorance of the population may undermine reliability on the product and immunization coverage, as observed in relation to the influenza vaccine in 2012.…”

“…Studies conducted in São Paulo and Teresina showed that the distribution of AEFI in this age group represented approximately 80% in relation to the other population segments. (7)(8)(9) In this sense, it is important to perform screening and monitoring following immunization so that AEFI are identified and intervention measures are adopted in a timely manner, enabling the maintenance of quality, safety of the vaccinees, and preservation of the reliability of the immunization. (1,9) AEFI should be carefully investigated aiming at avoiding a mismatch of cause and effect with the immunization, especially in cases presenting the occurrence of transitory association of the complication with the immunization.…”